Catalog |
name |
Description |
price |
R-R-1182 |
PI3K/mTOR Inhibitor-13 sodium CAS No.2361009-23-4 |
PI3K/mTOR Inhibitor-13 sodium/CAS No.2361009-23-4 is an orally active dual inhibitor of phosphoinositol 3-kinase (PI3K) and mTOR kinase. PI3K/mTOR Inhibitor-13 sodium has potential applications in sexual diseases, solid tumor and idiopathic pulmonary fibrosis (IPF). |
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R-R-1183 |
PI3K-IN-36 CAS No.1401436-93-8 |
PI3K-IN-36 (compound A36)/CAS No.1401436-93-8 is a potent PI3K inhibitor. PI3K-IN-36 can be used in research of follicular lymphoma (FL). |
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R-R-1184 |
3-Methyladenine-d3 CAS No.110953-39-4 |
3-Methyladenine-d3/CAS No.110953-39-4 is the deuterium labeled 3-Methyladenine[1]. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K. |
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R-R-1185 |
Idelalisib-d5 CAS No.1830330-31-8 |
Idelalisib-d5/CAS No.1830330-31-8 is a deuterium labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ inhibitor. |
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R-R-1186 |
Parsaclisib hydrochloride CAS No.1995889-48-9 |
Parsaclisib hydrochloride (INCB050465 hydrochloride)/CAS No.1995889-48-9 is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies. |
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R-R-1187 |
Pilaralisib analogue CAS No.956958-53-5 |
Pilaralisib analogue (XL147 analogue)/CAS No.956958-53-5 is a representative and selective PI3Kα inhibitor extracted from patent WO2012006552A1, Compound 147 in Table 1. |
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R-R-1188 |
Roginolisib hemifumarate CAS No.1621688-31-0 |
Roginolisib (MSC2360844) hemifumarate/CAS No.1621688-31-0 is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib hemifumarate shows highly selective against a panel of 278 additional kinases. |
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R-R-1189 |
PI3Kα-IN-9 CAS No.2715287-67-3 |
PI3Kα-IN-9 (compound 27)/CAS No.2715287-67-3 is a selective, long-acting and oral active PI3Kα inhibitor with IC50 values of 4.4, 128, 146 and 153 nM for PI3Kα, PI3Kγ, PI3Kδ and PI3Kβ, respectively. PI3Kα-IN-9 has antiproliferative activity and induces apoptosis. PI3Kα-IN-9 can be used for cancer research. |
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R-R-1190 |
NVS-PI3-4 CAS No.941580-60-5 |
NVS-PI3-4/CAS No.941580-60-5 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases. |
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R-R-1191 |
Methyllucidone CAS No.19956-54-8 |
Methyllucidone/CAS No.19956-54-8 is a neuroprotective agent and an antioxidant that can be isolated from Lindera erythrocarpa Makino. Methyllucidone inhibits the ROS production, and activates antioxidant signaling pathways that include Nrf-2 and PI3K. |
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