Product apis-metabolism

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Catalog	name	Description	price
R-C-554	MK 886 CAS: 118414-82-7	MK-886 is an inhibitor of leukotriene biosynthesis,inhibiting 5-lipoxygenase-activating protein (FLAP).It is also a moderately potent PPARα antagonist.	price>
R-C-578	LY315920 cas:172732-68-2	LY315920(Varespladib)is a potent and selective secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM.In BAL cells challenged with human sPLA2,LY315920 at doses ranging from 0.1 μM–3μM reduces the formation of thromboxane mediated by human sPLA2 in a concentration-dependent manner with an IC50 of approximately 0.8 μM.	price>
R-C-583	LY2608204 cas:1234703-40-2	LY2608204 is a potent used to treat type 2 diabetes.In a clinical trial,a study was performed to evaluate the safety and tolerability of LY2608204 in patients with type 2 diabetes.	price>
R-C-584	TAK-700 (Orteronel) cas:566939-85-3	TAK-700(Orteronel) is a potent and highly selective human 17,20-lyase inhibitor with IC50 of 38 nM,exhibits >1000-fold selectivity over other CYPs (e.g.11-hydroxylase and CYP3A4).TAK-700(Orteronel) is an androgen biosynthesis inhibitor.	price>
R-C-588	WAY362450 cas:629664-81-9	WAY-362450 is a highly potent, selective,and orally bioavailable farnesoid X receptor(FXR)agonist (EC50:4 nM,eff=149%).	price>
R-C-596	AGI-5198 cas:1355326-35-0	AGI-5198,also know as IDH-C35,is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.	price>
R-C-626	Rivaroxaban cas:366789-02-8	Rivaroxaban(BAY 59-7939)is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays,respectively. It is selective for human factor Xa,for which it has>10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20μM).	price>
R-C-628	SRPIN340 cas:218156-96-8	SRPIN340 is a cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50=0.14 and 1.8 μM,respectively,against mSRPK1 and mSRPK2)with much reduced activity against 143 other kinases.	price>
R-C-649	StemRegenin 1 (SR1) CAS No. 1227633-49-9	StemRegenin 1(SR1)is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).	price>
R-C-727	AdipoRon (SC-396658) CAS No. 924416-43-3	AdipoRon(SC-396658)is a novel, and orally bioavailable adiponectin receptor agonist with KD of 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively.	price>

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