Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-R-3427	Agomelatin-d3 CAS No.1079389-38-0	Agomelatin-d3/CAS No.1079389-38-0 is the deuterium labeled Agomelatine. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively.	price>
R-R-3428	Cinitapride CAS No.66564-14-5	Cinitapride/CAS No.66564-14-5 is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride can be used in functional dyspepsia (FD) and gastroesophageal reflux disease (GERD) research.	price>
R-R-3429	EMDT oxalate CAS No.263744-72-5	EMDT oxalate/CAS No.263744-72-5 is a selective 5-HT6 agonist, and has antidepressant effects.	price>
R-R-3430	Lerisetron CAS No.143257-98-1	Lerisetron/CAS No.143257-98-1 is a potent 5-HT3 antagonists and possess high-affinity binding for the 5-HT3 receptors with pKi value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats.	price>
R-C-1731	Vorapaxar (MK-5348) CAS: 618385-01-6	Vorapaxar(SCH 530348),an antiplatelet agent,is a selective,orally active,and competitive thrombin receptor protease-activated receptor(PAR-1)antagonist (Ki=8.1nM).Vorapaxar(SCH 530348)inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner.	price>
R-R-3431	Brexpiprazole-d8-1 CAS No.1427049-19-1	Brexpiprazole-d8-1/CAS No.1427049-19-1 is the deuterium labeled Brexpiprazole[1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM).	price>
R-R-3432	CP 93129 dihydrochloride CAS No.879089-64-2	CP 93129 dihydrochloride/CAS No.879089-64-2 is a potent 5HT1B receptor agonist. CP 93129 dihydrochloride has the potential for parkinson disease research.	price>
R-C-1734	Olopatadine Hydrochlorde CAS:140462-76-6	Olopatadine hydrochloride is a dual acting histamine H1-receptor antagonist and mast cell stabilizer.	price>
R-C-1737	Cloprostenol Sodium CAS:55028-72-3	Cloprostenol sodium salt(ICI 80996 sodium salt)is a potent synthetic prostaglandin analogue,acts as a luteolytic agent,and is a PGF2α receptor agonist.	price>
R-C-1764	PF429242 CAS：947303-87-9	PF 429242 is a reversible,competitive inhibitor of sterol regulatory element-binding protein(SREBP)site 1 protease.	price>

...

163