Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-C-1639	Cutamesine (SA4503; AGY-94806) CAS:165377-43-5	Cutamesine(SA4503;AGY-94806)is a selective sigma 1 receptor(σ1R)agonist; high affinity for the sigma 1 receptor subtype labeled by(+)-[3H]pentazocine(IC50= 17.4±1.9 nM)100-fold less affinity for the sigma 2 receptor.	price>
R-R-3345	Ro60-0175 fumarate CAS No.169675-09-6	Ro60-0175 fumarate/CAS No.169675-09-6 is a potent and selective agonist of 5-HT2C receptor.	price>
R-R-3346	(S)-Amisulpride CAS No.71675-92-8	(S)-Amisulpride (Esamisulpride)/CAS No.71675-92-8 is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.	price>
R-R-3347	SB228357 CAS No.181629-93-6	SB228357/CAS No.181629-93-6 is a selective, potent and orall active 5-HT2C/2B receptor antagonist with pKi values of 6.9, 8.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effects.	price>
R-R-3348	SB-200646A CAS No.143797-62-0	SB-200646A/CAS No.143797-62-0 is the first selective 5-HT2B/2C over 5-HT2A receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646A is orally active and has electrophysiological and anxiolytic properties in vivo.	price>
R-R-3349	PU02 CAS No.313984-77-9	PU02/CAS No.313984-77-9, a derivative of 6-MP (HY-13677), is a negative allosteric modulator (NAM) of 5-HT3 receptor, with IC50 values of 0.36 and 0.73 μM in HEK293 cells transfected with human 5-HT3A and 5-HT3AB receptors respectively.	price>
R-R-3350	Alniditan dihydrochloride CAS No.155428-00-5	Alniditan (Alnitidan) dihydrochloride/CAS No.155428-00-5 is a potent 5-HT1B and 5-HT1D receptors agonist, with IC50s of 1.7 nM and 1.3 nM for h5-HT1B and h5-HT1D receptors in HEK 293 cells, respectively. Alniditan dihydrochloride has migraine-preventive effects.	price>
R-R-3351	Tedatioxetine hydrobromide CAS No.960151-65-9	Tedatioxetine (Lu AA24530) hydrobromide/CAS No.960151-65-9 acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist.	price>
R-R-3352	Naluzotan CAS No.740873-06-7	Naluzotan/CAS No.740873-06-7 is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of 3800 nM.	price>
R-C-1653	Eptapirone (F11440) CAS：179756-58-2	Eptapirone(F11440)is a potent,selective,high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.	price>

...

163