Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3320	OPC-14523 hydrochloride CAS No.145969-31-9	OPC-14523 hydrochloride/CAS No.145969-31-9 is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity.	price>
R-R-3321	Clozapine-d4 CAS No.204395-52-8	Clozapine-d4/CAS No.204395-52-8 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors.	price>
R-R-3322	F 13714 fumarate CAS No.208109-39-1	F13714 fumarate/CAS No.208109-39-1, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress.	price>
R-R-3323	CJ033466 CAS No.519148-48-2	CJ033466/CAS No.519148-48-2 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect.	price>
R-R-3324	(Rac)-WAY-161503 CAS No.75704-24-4	(Rac)-WAY-161503/CAS No.75704-24-4 is a potent, selective, highly affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects.	price>
R-C-1625	Sotagliflozin (LX4211) CAS：1018899-04-1	Sotagliflozin（LX4211)is an orally active and a dual SGLT1/SGLT2 inhibitor, which improves glycemic control in patients with type 2 diabetes in a randomized,placebo-controlled trial.LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1(SGLT1)-mediated absorption of intestinal glucose.	price>
R-R-3325	RU 24969 succinate CAS No.107008-28-6	RU 24969 succinate/CAS No.107008-28-6 is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease.	price>
R-R-3326	Almotriptan CAS No.154323-57-6	Almotriptan/CAS No.154323-57-6 is a selective agonist of 5-HT 1B/1D Receptor. Almotriptan can used in study of migraine attacks.	price>
R-R-3327	GR-46611 CAS No.185259-85-2	GR-46611/CAS No.185259-85-2 is a 5-HT1D receptor agonist. GR-46611 can be used in the research of bladder hyperactivity, leukemia.	price>
R-C-1638	PIBOSEROD CAS# 152811-62-6	Piboserod(SB-207266)is a selective 5-HT4 receptor antagonist which was marketed and manufactured by GlaxoSmithKline(GSK)under the trade name Serlipet for the management of atrial fibrillation and irritable bowel syndrome.In 2007 the Norwegian company Bio-Medisinsk Innovasjon AS(BMI)completed a clinical phase II study to investigate the effect of piboserod in patients with chronic heart failure.	price>

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