Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3324	(Rac)-WAY-161503 CAS No.75704-24-4	(Rac)-WAY-161503/CAS No.75704-24-4 is a potent, selective, highly affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects.	price>
R-C-1625	Sotagliflozin (LX4211) CAS：1018899-04-1	Sotagliflozin（LX4211)is an orally active and a dual SGLT1/SGLT2 inhibitor, which improves glycemic control in patients with type 2 diabetes in a randomized,placebo-controlled trial.LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1(SGLT1)-mediated absorption of intestinal glucose.	price>
R-R-3325	RU 24969 succinate CAS No.107008-28-6	RU 24969 succinate/CAS No.107008-28-6 is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease.	price>
R-R-3326	Almotriptan CAS No.154323-57-6	Almotriptan/CAS No.154323-57-6 is a selective agonist of 5-HT 1B/1D Receptor. Almotriptan can used in study of migraine attacks.	price>
R-R-3327	GR-46611 CAS No.185259-85-2	GR-46611/CAS No.185259-85-2 is a 5-HT1D receptor agonist. GR-46611 can be used in the research of bladder hyperactivity, leukemia.	price>
R-C-1638	PIBOSEROD CAS# 152811-62-6	Piboserod(SB-207266)is a selective 5-HT4 receptor antagonist which was marketed and manufactured by GlaxoSmithKline(GSK)under the trade name Serlipet for the management of atrial fibrillation and irritable bowel syndrome.In 2007 the Norwegian company Bio-Medisinsk Innovasjon AS(BMI)completed a clinical phase II study to investigate the effect of piboserod in patients with chronic heart failure.	price>
R-C-1639	Cutamesine (SA4503; AGY-94806) CAS:165377-43-5	Cutamesine(SA4503;AGY-94806)is a selective sigma 1 receptor(σ1R)agonist; high affinity for the sigma 1 receptor subtype labeled by(+)-[3H]pentazocine(IC50= 17.4±1.9 nM)100-fold less affinity for the sigma 2 receptor.	price>
R-R-3345	Ro60-0175 fumarate CAS No.169675-09-6	Ro60-0175 fumarate/CAS No.169675-09-6 is a potent and selective agonist of 5-HT2C receptor.	price>
R-R-3346	(S)-Amisulpride CAS No.71675-92-8	(S)-Amisulpride (Esamisulpride)/CAS No.71675-92-8 is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.	price>
R-R-3347	SB228357 CAS No.181629-93-6	SB228357/CAS No.181629-93-6 is a selective, potent and orall active 5-HT2C/2B receptor antagonist with pKi values of 6.9, 8.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effects.	price>

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