Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3280	YM348 CAS No.372163-84-3	YM348/CAS No.372163-84-3 is a potent and orally active 5-HT2C receptor agonist, which shows a high affinity for cloned human 5-HT2C receptor (Ki: 0.89 nM).	price>
R-R-3281	ST1936 CAS No.1210-81-7	ST1936/CAS No.1210-81-7 is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively. ST1936 also shows moderate affinity (Ki of 300 nM) for human and rat α2 adrenergic receptor.	price>
R-C-1581	NU7026 CAS:154447-35-5	NU7026(LY293646)is a potent DNA-PK inhibitor with IC50 of 0.23 μM in cell-free assays,60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR.NU7026 enhances G2/M cell arrest and apoptosis.	price>
R-R-3282	(S)-Mirtazapine CAS No.61337-87-9	(S)-Mirtazapine ((S)-Org3770)/CAS No.61337-87-9 is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2.	price>
R-R-3283	Repinotan hydrochloride CAS No.144980-77-8	Repinotan hydrochloride (BAY x 3702)/CAS No.144980-77-8 is a potent, selective, brain-penetrant and orally active 5-HT1A receptor agonist, with Ki values of 0.19 nM (calf hippocampus), 0.25 nM (rat and human cortex), and 0.59 nM (rat hippocampus Repinotan hydrochloride has a weak affinity for other related receptors. Repinotan hydrochloride has pronounced neuroprotective effects.	price>
R-R-3284	Clothiapine CAS No.2058-52-8	Clothiapine/CAS No.2058-52-8, an atypical antipsychotic agent, shares with clozapine its strong antiserotonergic properties.	price>
R-R-3285	Renzapride CAS No.112727-80-7	Renzapride (BRL 24924)/CAS No.112727-80-7, a substituted benzamide, is a full 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride (BRL 24924) is also a 5HT2b and 5HT3 receptor antagonist. Renzapride could be used for constipation predominant irritable bowel syndrome (C-IBS) study.	price>
R-R-3286	Dolasetron Mesylate hydrate CAS No.878143-33-0	Dolasetron Mesylate hydrate (MDL-73147EF hydrate)/CAS No.878143-33-0 is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.	price>
R-R-3287	Ampreloxetine TFA	Ampreloxetine (TD-9855) TFA is a potent and orally active norepinephrine (NE) and serotonin 5-HT inhibitor. Ampreloxetine TFA has the potential for the research of neurogenic orthostatic hypotension.	price>
R-R-3288	BRL-15572 dihydrochloride CAS No.193611-72-2	BRL-15572 dihydrochloride/CAS No.193611-72-2 is a selective antagonist of h5-HT1D, displays high affinity for h5-HT1D receptors. BRL-15572 dihydrochloride could be useful pharmacological agents to characterise 5-HT1D receptor mediated responses.	price>

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