Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-C-1559	CCG215022 CAS：1813527-81-9	CCG215022 is a potent GRK2 and GRK5 inhibitor.CCG215022 exhibited nanomolar IC50 values against both GRK2 and GRK5 and good selectivity against other closely related kinases such as GRK1 and PKA.	price>
R-R-3259	m-CPBG hydrochloride CAS No.2113-05-5	m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride/CAS No.2113-05-5 is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease.	price>
R-R-3260	RS 39604 CAS No.167710-87-4	RS 39604/CAS No.167710-87-4 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. RS 39604 displays a low affinity (pKi<6.5) for 5-HT1A, 5-HT2C, 5-HT3, α1c, D1, D2, M1, M2, AT1, B1 and opioid mu receptors and moderate affinity for δ1, (pKi=6.8) and δ2 (pKi=7.8) sites.	price>
R-R-3261	Quetiapine-d4 hemifumarate CAS No.1217310-65-0	Quetiapine-d4 (hemifumarate)/CAS No.1217310-65-0 is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a 5-HT receptors agonist and a dopamine receptor antagonist. Antidepressant and anxiolytic effects.	price>
R-R-3262	WAY-100135 dihydrochloride CAS No.149055-79-8	WAY-100135 dihydrochloride/CAS No.149055-79-8 is a selective antagonist at presynaptic and postsynaptic 5-HT1A receptor, with an IC50 of 34 nM at the rat hippocampal 5-HT1A receptor. WAY-100135 dihydrochloride has potential antipsychotic properties.	price>
R-R-3263	7-Desmethyl-agomelatine CAS No.152302-45-9	7-Desmethyl-agomelatine/CAS No.152302-45-9 is a metabolite of Agomelatine. Agomelatineis a potent agonist at melatonin receptors (MT1 and MT2), and also is an antagonist of 5-HT2C.	price>
R-R-3264	Donitriptan CAS No.170912-52-4	Donitriptan/CAS No.170912-52-4 is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively.	price>
R-C-1565	Relugolix (TAK-385) CAS：737789-87-6	Relugolix(RVT-601,TAK-385)is a selective antagonist of the gonadotropin-releasing hormone receptor(GnRHR)with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR,respectively.	price>
R-R-3265	Strictosidinic acid CAS No.150148-81-5	Strictosidinic acid/CAS No.150148-81-5, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice.	price>
R-R-3266	Felcisetrag CAS No.916075-84-8	Felcisetrag (TD-8954)/CAS No.916075-84-8 is an orally active, potent and selective 5-HT4 receptor agonist with gastrointestinal prokinetic properties. Felcisetrag has high affinity (pKi =9.4) for human 5-HT4(c) receptors.	price>

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