Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-R-3252	SB-616234-A CAS No.908601-49-0	SB-616234-A/CAS No.908601-49-0 is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity.	price>
R-C-1553	Bay 59-3074 CAS:406205-74-1	Bay 59-3074 is a selective cannabinoid CB1/CB2 receptor partial agonist with Ki of 55.4 nM,48.3 nM and 45.5nM at rat and human CB1 and human CB2 receptors, respectively.Bay 59-3074 displays analgesic properties.	price>
R-R-3253	Spiramide CAS No.510-74-7	Spiramide (AMI-193)/CAS No.510-74-7 is a potent and selective antagonist of 5-HT2 and dopamine D2 receptor, with Kis of 2 nM and 3 nM, respectively. Spiramide has >2000-fold selectivity for 5-HT2 versus 5-HT1C (Ki=4300 nM) receptors. Spiramide exhibits antipsychotic activity.	price>
R-R-3254	Cerlapirdine CAS No.925448-93-7	Cerlapirdine (SAM-531, PF-05212365)/CAS No.925448-93-7 is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor.	price>
R-R-3255	Usmarapride CAS No.1428862-33-2	Usmarapride (SUVN-D4010)/CAS No.1428862-33-2 is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM).	price>
R-R-3256	Usmarapride free base CAS No.1428862-32-1	Usmarapride (SUVN-D4010) free base/CAS No.1428862-32-1 is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM).	price>
R-R-3257	Ampreloxetine CAS No.1227056-84-9	Ampreloxetine (TD-9855)/CAS No.1227056-84-9 is a potent and orally active norepinephrine (NE) and serotonin 5-HT inhibitor. Ampreloxetine has the potential for the research of neurogenic orthostatic hypotension.	price>
R-R-3258	Amitriptyline-d6 hydrochloride CAS No.203645-63-0	Amitriptyline-d6 (hydrochloride)/CAS No.203645-63-0 is the deuterium labeled Amitriptyline hydrochloride. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity.	price>
R-C-1559	CCG215022 CAS：1813527-81-9	CCG215022 is a potent GRK2 and GRK5 inhibitor.CCG215022 exhibited nanomolar IC50 values against both GRK2 and GRK5 and good selectivity against other closely related kinases such as GRK1 and PKA.	price>
R-R-3259	m-CPBG hydrochloride CAS No.2113-05-5	m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride/CAS No.2113-05-5 is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease.	price>

...

163