Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3213	Urapidil hydrochloride CAS No.64887-14-5	Urapidil hydrochloride/CAS No.64887-14-5 is an orally active α1-adrenoceptor antagonist and 5-HT1A receptor agonist with a pIC50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect.	price>
R-R-3214	Ecopipam hydrobromide CAS No.2587360-22-1	Ecopipam (SCH 39166) hydrobromide/CAS No.2587360-22-1 is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrobromide shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrobromide can be used for the research of schizophrenia and obesity.	price>
R-R-3215	PRX-08066 CAS No.866206-54-4	PRX-08066/CAS No.866206-54-4 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.	price>
R-R-3216	Befiradol CAS No.208110-64-9	Befiradol (NLX-112)/CAS No.208110-64-9 is a selective 5-HT1A receptor agonist.	price>
R-R-3217	Melitracen hydrochloride CAS No.10563-70-9	Melitracen hydrochloride/CAS No.10563-70-9 is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space.	price>
R-R-3218	Piromelatine CAS No.946846-83-9	Piromelatine (Neu-P11)/CAS No.946846-83-9 is a melatonin MT1/MT2 receptor agonist, serotonin 5-HT1A/5-HT1D agonist, and serotonin 5-HT2B antagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic and antidepressant potentials. Piromelatine (Neu-P11) also possesses pain-related P2X3, TRPV1, and Nav1.7 channel-inhibition capacities.	price>
R-R-3219	Geissoschizine methyl ether CAS No.60314-89-8	Geissoschizine methyl ether/CAS No.60314-89-8, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist.	price>
R-R-3220	Tianeptine CAS No.72797-41-2	Tianeptine/CAS No.72797-41-2 is a selective facilitator of 5-HT uptake. Tianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50>10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine has antidepressant, anxiolytic, analgesic and neuroprotective activities.	price>
R-R-3221	MK-212 monohydrochloride CAS No.61655-58-1	MK-212 (CPP) monohydrochloride/CAS No.61655-58-1 is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex.	price>
R-R-3222	Vabicaserin hydrochloride CAS No.887258-94-8	Vabicaserin hydrochloride/CAS No.887258-94-8 is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.	price>

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