Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3159	SB 258719 CAS No.195199-95-2	SB 258719/CAS No.195199-95-2 is a selective 5-HT7 receptor antagonist with high affinity (pKi=7.5) for the receptor. SB 258719 can be used for the research of cancer and neurological disease.	price>
R-R-3160	Ziprasidone hydrochloride monohydrate CAS No.138982-67-9	Ziprasidone (CP-88059) hydrochloride monohydrate/CAS No.138982-67-9 is an orally active combined 5-HT and dopamine receptor antagonist. Ziprasidone hydrochloride monohydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM).	price>
R-R-3161	Jatrorrhizine hydroxide CAS No.483-43-2	Jatrorrhizine hydroxide/CAS No.483-43-2 is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE. Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters.	price>
R-R-3162	Gepirone CAS No.83928-76-1	Gepirone/CAS No.83928-76-1 is a selective and affinitive 5-HT1A agonist. Gepirone binds selectively to 5-HT1A receptor binding site. Gepirone acts as an antidepressant agent can be used for anxiety and major depressive disorder research.	price>
R-R-3163	Asenapine CAS No.65576-45-6	Asenapine (Org 5222)/CAS No.65576-45-6, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine can be used in the research of schizophrenia and bipolar disorder.	price>
R-R-3164	RU 24969 CAS No.66611-26-5	RU 24969/CAS No.66611-26-5 is a preferential 5-HT1B agonist, with a Ki of 0.38 nM, but also displays appreciable affinity for the 5-HT1A receptor (Ki=2.5 nM), and has low affinity for other receptor sites in the brain. RU 24969 could decrease fluid consumption and increase forward locomotion.	price>
R-R-3165	Rotigotine Hydrochloride CAS No.125572-93-2	Rotigotine Hydrochloride (N-0923 Hydrochloride)/CAS No.125572-93-2 is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.	price>
R-R-3166	Tianeptine sodium salt CAS No.30123-17-2	Tianeptine sodium salt/CAS No.30123-17-2 is a selective facilitator of 5-HT uptake. Tianeptine sodium salt has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50>10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine sodium salt has antidepressant, anxiolytic, analgesic and neuroprotective activities.	price>
R-R-3167	Rizatriptan benzoate CAS No.145202-66-0	Rizatriptan Benzoate(Maxalt)/CAS No.145202-66-0 is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.	price>
R-R-3168	Nefazodone CAS No.83366-66-9	Nefazodone/CAS No.83366-66-9 is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT2A receptors, and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction.	price>

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