Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3148	Harmine hydrochloride CAS No.343-27-1	Harmine Hydrochloride (Telepathine Hydrochloride)/CAS No.343-27-1 is a natural DYRK inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM.	price>
R-R-3149	Perospirone CAS No.150915-41-6	Perospirone (SM-9018 free base)/CAS No.150915-41-6 is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research.	price>
R-R-3150	AS19 CAS No.1000578-26-6	AS19/CAS No.1000578-26-6 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia.	price>
R-R-3151	2-Methyl-5-HT CAS No.78263-90-8	2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine)/CAS No.78263-90-8 is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects.	price>
R-R-3152	Oxatomide CAS No.60607-34-3	Oxatomide/CAS No.60607-34-3 is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin.	price>
R-R-3153	CP94253 hydrochloride CAS No.845861-39-4	CP94253 hydrochloride/CAS No.845861-39-4 is a potent and selective agonist of 5-HT1B receptor (Ki= 2 nM in a radioligand binding assay).Ki values for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors are 89, 49, 860, and 1600 nM respectively. CP94253 hydrochloride is centrally active upon systemic administration in vivo.	price>
R-R-3154	Setiptiline CAS No.57262-94-9	Setiptiline (Org-8282)/CAS No.57262-94-9 is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.	price>
R-R-3155	Setiptiline maleate CAS No.85650-57-3	Setiptiline maleate (MO-8282 maleate)/CAS No.85650-57-3 is a serotonin receptor antagonist. Setiptiline maleate is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline maleate acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.	price>
R-C-1456	NSC19005(Betahistine EP Impurity C) CAS:5452-87-9	Betahistine EP Impurity C(NSC19005)is an impurity of Betahistine.Betahistine is a potent,orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis(RA).	price>
R-R-3156	Lumateperone tosylate CAS No.1187020-80-9	Lumateperone (ITI-007) tosylate/CAS No.1187020-80-9 is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.	price>

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