Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3152	Oxatomide CAS No.60607-34-3	Oxatomide/CAS No.60607-34-3 is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin.	price>
R-R-3153	CP94253 hydrochloride CAS No.845861-39-4	CP94253 hydrochloride/CAS No.845861-39-4 is a potent and selective agonist of 5-HT1B receptor (Ki= 2 nM in a radioligand binding assay).Ki values for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors are 89, 49, 860, and 1600 nM respectively. CP94253 hydrochloride is centrally active upon systemic administration in vivo.	price>
R-R-3154	Setiptiline CAS No.57262-94-9	Setiptiline (Org-8282)/CAS No.57262-94-9 is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.	price>
R-R-3155	Setiptiline maleate CAS No.85650-57-3	Setiptiline maleate (MO-8282 maleate)/CAS No.85650-57-3 is a serotonin receptor antagonist. Setiptiline maleate is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline maleate acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.	price>
R-C-1456	NSC19005(Betahistine EP Impurity C) CAS:5452-87-9	Betahistine EP Impurity C(NSC19005)is an impurity of Betahistine.Betahistine is a potent,orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis(RA).	price>
R-R-3156	Lumateperone tosylate CAS No.1187020-80-9	Lumateperone (ITI-007) tosylate/CAS No.1187020-80-9 is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.	price>
R-R-3157	(Z)-Thiothixene CAS No.3313-26-6	(Z)-Thiothixene/CAS No.3313-26-6 is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.	price>
R-R-3158	Eletriptan hydrobromide CAS No.177834-92-3	Eletriptan hydrobromide (Eletriptan HBr)/CAS No.177834-92-3 is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.	price>
R-R-3159	SB 258719 CAS No.195199-95-2	SB 258719/CAS No.195199-95-2 is a selective 5-HT7 receptor antagonist with high affinity (pKi=7.5) for the receptor. SB 258719 can be used for the research of cancer and neurological disease.	price>
R-R-3160	Ziprasidone hydrochloride monohydrate CAS No.138982-67-9	Ziprasidone (CP-88059) hydrochloride monohydrate/CAS No.138982-67-9 is an orally active combined 5-HT and dopamine receptor antagonist. Ziprasidone hydrochloride monohydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM).	price>

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