Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-R-2978	ML-098 CAS No.878978-76-8	ML-098 (CID-7345532)/CAS No.878978-76-8 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM.	price>
R-R-2979	RAS-IN-2 CAS No.2765081-21-6	RAS-IN-2 (Compound A122)/CAS No.2765081-21-6 is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.	price>
R-R-2980	MRTX-1257 CAS No.2206736-04-9	MRTX-1257/CAS No.2206736-04-9 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.	price>
R-R-2981	FTI-277 hydrochloride CAS No.180977-34-8	FTI-277 hydrochloride/CAS No.180977-34-8 is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. FTI-277 hydrochloride can inhibit hepatitis delta virus (HDV) infection.	price>
R-R-2982	Sotorasib racemate CAS No.2252403-56-6	Sotorasib racemate (Compound A)/CAS No.2252403-56-6 is an orally active racemate of Sotorasib (HY-114277), a covalent inhibitor of KRAS G12C mutant which induces adaptive feedback activation of MAPK pathway. Sotorasib racemate also exerts inhibitor activity against KRAS G12C induced cancer and can be applied to cancer research.	price>
R-R-2983	Pan-RAS-IN-1 CAS No.1835283-94-7	Pan-RAS-IN-1/CAS No.1835283-94-7 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors.	price>
R-R-2984	BDP9066 CAS No.2226507-04-4	BDP9066/CAS No.2226507-04-4 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with an IC50 of 64 nM for MRCKβ in SCC12 cells, Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively. BDP9066 has therapeutic effect on skin cancer by reducing substrate phosphorylation.	price>
R-R-2985	CCG-222740 CAS No.1922098-69-8	CCG-222740/CAS No.1922098-69-8 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor. CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. CCG-222740 effectively reduces fibrosis in skin and blocks melanoma metastasis.	price>
R-R-2986	PROTAC K-Ras Degrader-1 CAS No.2378258-52-5	PROTAC K-Ras Degrader-1 (Compound 518)/CAS No.2378258-52-5 is a PROTAC. PROTAC K-Ras Degrader-1 can effectively degrades K-Ras based on Cereblon E3 ligand, exhibits ≥70% degradation efficacy in SW1573 cells.	price>
R-R-2987	ML-099 CAS No.496775-95-2	ML-099 (CID-888706)/CAS No.496775-95-2 is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A.	price>

...

163