Products classification
ABOUT US
Email:
sales@ruixibiotech.com
Tel.:
02988811435
Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4334 UNC9995 CAS No.1354030-52-6 UNC9995/CAS No.1354030-52-6 is a β-arrestin2-biased agonist of dopamine receptor Drd2. UNC9995 inhibits NLRP3 inflammasome activation by enhancing β-arrestin2-NLRP3 interaction, thus prevents neuronal degeneration. Futhermore, UNC9995 activates the Drd2/β-arrestin2 signaling to prevent inflammation-related genes transcription-induced by JAK/STAT3. UNC9995 improves depressive behavior in mouse model, and improves astrocytes dysfunctions. price>
R-R-4335 SKF 83822 CAS No.74115-08-5 SKF 83822/CAS No.74115-08-5 is an atypical agonist of dopamine D1 receptor. SKF 83822 activates adenylyl cyclase (AC), but not phospholipase C (PLC). SKF 83822 is also proved to stimulate AC via cAMP production. SKF 83822 can be used for research of schizophrenia. price>
R-R-4336 Rimcazole dihydrochloride CAS No.75859-03-9 Rimcazole (BW 234U) dihydrochloride/CAS No.75859-03-9 is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. Rimcazole dihydrochloride also binds with moderate affinity to the dopamine transporter and inhibit dopamine uptake. Rimcazole dihydrochloride can reduce locomotor activity and sensitization. Rimcazole dihydrochloride also can be used for the research of cancer. price>
R-R-4337 SKF 83959 hydrobromide CAS No.67287-95-0 SKF83959 hydrobromide/CAS No.67287-95-0 is a potent and selective dopamine D1-like receptor partial agonist. SKF83959 hydrobromide Ki values for rat D1, D5, D2 and D3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 hydrobromide belongs to benzazepine family and has improvements on cognitive dysfunction. price>
R-R-4338 PF-06256142 CAS No.1609583-14-3 PF-06256142/CAS No.1609583-14-3 is a potent, selective, CNS-penetrant and orally active agonist of the D1 receptor, with an EC50 and Ki of 33 nM and 12 nM, respectively. price>
R-R-4339 Tavapadon CAS No.1643489-24-0 Tavapadon (PF-06649751)/CAS No.1643489-24-0 is an orally active and highly selective dopamine D1/D5 receptor partial agonist. price>
R-R-4340 Mesdopetam hemitartrate CAS No.2562346-14-7 Mesdopetam (IRL790) hemitartrate/CAS No.2562346-14-7 is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate is used for the research of motor and psychiatric complications in Parkinson disease. price>
R-R-4341 Dopamine D2 receptor antagonist-1 CAS No.1055411-77-2 Dopamine D2 receptor antagonist-1/CAS No.1055411-77-2 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity. price>
R-R-4342 Propionylpromazine hydrochloride CAS No.7681-67-6 Propionylpromazine hydrochloride (Propiopromazine hydrochloride)/CAS No.7681-67-6, a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease. price>
R-R-4343 Quinelorane dihydrochloride CAS No.97548-97-5 Quinelorane dihydrochloride (LY163502)/CAS No.97548-97-5 is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research. price>