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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4314 Amisulpride CAS No.71675-85-9 Amisulpride/CAS No.71675-85-9 is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively. price>
R-R-4315 Clebopride malate CAS No.57645-91-7 Clebopride malate/CAS No.57645-91-7 is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. price>
R-R-4316 Nomifensine maleate CAS No.32795-47-4 Nomifensine maleate/CAS No.32795-47-4 is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder. price>
R-R-4317 Pridopidine CAS No.346688-38-8 Pridopidine/CAS No.346688-38-8, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is ~100× higher than its affinity toward D2R. price>
R-R-4318 Dexpramipexole dihydrochloride CAS No.104632-27-1 Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride)/CAS No.104632-27-1 is a neuroprotective agent and weak non-ergoline dopamine agonist. price>
R-R-4319 LY3154207 CAS No.1638667-79-4 LY3154207/CAS No.1638667-79-4 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM). price>
R-R-4320 GSK598809 CAS No.863680-45-9 GSK598809/CAS No.863680-45-9 is a potent and selective dopamine D3 Receptor (DRD3) antagonist, with a pKi of 8.9. price>
R-R-4321 L-745870 CAS No.158985-00-3 L-745870/CAS No.158985-00-3 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors. price>
R-R-4322 Tiapride hydrochloride CAS No.51012-33-0 Tiapride hydrochloride/CAS No.51012-33-0 is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent. price>
R-R-4323 MLS1547 CAS No.315698-36-3 MLS1547/CAS No.315698-36-3 is a highly efficacious G protein-biased dopamine D2 receptor (D2R) agonist (Ki=1.2 μM). MLS1547 stimulates D2R G protein-mediated signaling (EC50=0.37 μM in a calcium mobilization assay). MLS1547 acts as an antagonist for dopamine (DA)-stimulated β-arrestin recruitment to the D2R (IC50=9.9 μM). price>