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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4318 Dexpramipexole dihydrochloride CAS No.104632-27-1 Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride)/CAS No.104632-27-1 is a neuroprotective agent and weak non-ergoline dopamine agonist. price>
R-R-4319 LY3154207 CAS No.1638667-79-4 LY3154207/CAS No.1638667-79-4 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM). price>
R-R-4320 GSK598809 CAS No.863680-45-9 GSK598809/CAS No.863680-45-9 is a potent and selective dopamine D3 Receptor (DRD3) antagonist, with a pKi of 8.9. price>
R-R-4321 L-745870 CAS No.158985-00-3 L-745870/CAS No.158985-00-3 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors. price>
R-R-4322 Tiapride hydrochloride CAS No.51012-33-0 Tiapride hydrochloride/CAS No.51012-33-0 is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent. price>
R-R-4323 MLS1547 CAS No.315698-36-3 MLS1547/CAS No.315698-36-3 is a highly efficacious G protein-biased dopamine D2 receptor (D2R) agonist (Ki=1.2 μM). MLS1547 stimulates D2R G protein-mediated signaling (EC50=0.37 μM in a calcium mobilization assay). MLS1547 acts as an antagonist for dopamine (DA)-stimulated β-arrestin recruitment to the D2R (IC50=9.9 μM). price>
R-R-4324 Halopemide CAS No.59831-65-1 Halopemide/CAS No.59831-65-1 is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent. price>
R-R-4325 (+)-PD 128907 hydrochloride CAS No.300576-59-4 (+)-PD 128907 hydrochloride/CAS No.300576-59-4 is a selective dopamine D2/D3 receptor agonist, with Kis of 1.7, 0.84 nM for human and rat D3 receptors, 179, 770 n M for human and rat D3 receptors, respectively. price>
R-R-4326 Pericyazine CAS No.2622-26-6 Pericyazine (Propericiazine)/CAS No.2622-26-6 is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects. price>
R-R-4327 Eticlopride hydrochloride CAS No.97612-24-3 Eticlopride hydrochloride/CAS No.97612-24-3, a selective dopamine D2‐like receptor antagonist, exhibits high affinity for dopamine D2, α1‐adrenergic, α2‐adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Antipsychotic agent. price>