Catalog |
name |
Description |
price |
R-R-4317 |
Pridopidine CAS No.346688-38-8 |
Pridopidine/CAS No.346688-38-8, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is ~100× higher than its affinity toward D2R. |
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R-R-4318 |
Dexpramipexole dihydrochloride CAS No.104632-27-1 |
Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride)/CAS No.104632-27-1 is a neuroprotective agent and weak non-ergoline dopamine agonist. |
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R-R-4319 |
LY3154207 CAS No.1638667-79-4 |
LY3154207/CAS No.1638667-79-4 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM). |
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R-R-4320 |
GSK598809 CAS No.863680-45-9 |
GSK598809/CAS No.863680-45-9 is a potent and selective dopamine D3 Receptor (DRD3) antagonist, with a pKi of 8.9. |
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R-R-4321 |
L-745870 CAS No.158985-00-3 |
L-745870/CAS No.158985-00-3 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors. |
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R-R-4322 |
Tiapride hydrochloride CAS No.51012-33-0 |
Tiapride hydrochloride/CAS No.51012-33-0 is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent. |
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R-R-4323 |
MLS1547 CAS No.315698-36-3 |
MLS1547/CAS No.315698-36-3 is a highly efficacious G protein-biased dopamine D2 receptor (D2R) agonist (Ki=1.2 μM). MLS1547 stimulates D2R G protein-mediated signaling (EC50=0.37 μM in a calcium mobilization assay). MLS1547 acts as an antagonist for dopamine (DA)-stimulated β-arrestin recruitment to the D2R (IC50=9.9 μM). |
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R-R-4324 |
Halopemide CAS No.59831-65-1 |
Halopemide/CAS No.59831-65-1 is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent. |
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R-R-4325 |
(+)-PD 128907 hydrochloride CAS No.300576-59-4 |
(+)-PD 128907 hydrochloride/CAS No.300576-59-4 is a selective dopamine D2/D3 receptor agonist, with Kis of 1.7, 0.84 nM for human and rat D3 receptors, 179, 770 n M for human and rat D3 receptors, respectively. |
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R-R-4326 |
Pericyazine CAS No.2622-26-6 |
Pericyazine (Propericiazine)/CAS No.2622-26-6 is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects. |
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