Products classification
ABOUT US
Email:
sales@ruixibiotech.com
Tel.:
02988811435
Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4324 Halopemide CAS No.59831-65-1 Halopemide/CAS No.59831-65-1 is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent. price>
R-R-4325 (+)-PD 128907 hydrochloride CAS No.300576-59-4 (+)-PD 128907 hydrochloride/CAS No.300576-59-4 is a selective dopamine D2/D3 receptor agonist, with Kis of 1.7, 0.84 nM for human and rat D3 receptors, 179, 770 n M for human and rat D3 receptors, respectively. price>
R-R-4326 Pericyazine CAS No.2622-26-6 Pericyazine (Propericiazine)/CAS No.2622-26-6 is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects. price>
R-R-4327 Eticlopride hydrochloride CAS No.97612-24-3 Eticlopride hydrochloride/CAS No.97612-24-3, a selective dopamine D2‐like receptor antagonist, exhibits high affinity for dopamine D2, α1‐adrenergic, α2‐adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Antipsychotic agent. price>
R-R-4328 Azaperone CAS No.1649-18-9 Azaperone (R-1929)/CAS No.1649-18-9 acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. price>
R-R-4329 (±)-Levomepromazine-d6 CAS No.1189805-51-3 (±)-Levomepromazine-d6/CAS No.1189805-51-3 is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist. price>
R-R-4330 UCSF924 CAS No.1434515-70-4 UCSF924/CAS No.1434515-70-4 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has a high-affinity with a Ki value of 3 nM for DRD4 and shows no measurable affinity for D2, D3 or the F261V/L328F D4 mutant. UCSF924 is a 7.4-fold bias toward arrestin over Gαi/o signaling, referenced to quinpirole. price>
R-R-4331 SKF 83959 CAS No.80751-85-5 SKF83959/CAS No.80751-85-5 is a potent and selective dopamine D1-like receptor partial agonist. SKF83959 Ki values for rat D1, D5, D2 and D3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 belongs to benzazepine family and has improvements on cognitive dysfunction. price>
R-R-4332 Roxindole hydrochloride CAS No.108050-82-4 Roxindole hydrochloride (EMD 38362)/CAS No.108050-82-4, an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities. price>
R-R-4333 3-O-Methyldopa-d3 CAS No.586954-09-8 3-O-Methyldopa-d3/CAS No.586954-09-8 is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine. price>