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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4158 TAK-779 CAS No.229005-80-5 TAK-779/CAS No.229005-80-5 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells. price>
R-R-4159 Zelnecirnon CAS No.2366152-15-8 Zelnecirnon (RPT193)/CAS No.2366152-15-8 is an orally active inhibitor of CCR4, blocks the recruitment of Th2 inflammatory immune cells into inflamed tissues. Zelnecirnon can be used for allergic inflammation in atopic dermatitis, asthma, and other diseases research. price>
R-R-4160 CCR6 antagonist 1 CAS No.588674-64-0 CCR6 antagonist 1/CAS No.588674-64-0 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs). price>
R-R-4161 CCR6 inhibitor 1 CAS No.2437547-04-9 CCR6 inhibitor 1/CAS No.2437547-04-9 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer. price>
R-R-4162 AZD2098 CAS No.566203-88-1 AZD2098/CAS No.566203-88-1 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research. price>
R-R-4163 ZK756326 dihydrochloride CAS No.1780259-94-0 ZK756326 dihydrochloride/CAS No.1780259-94-0 is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8. price>
R-R-4164 AZ084 CAS No.929300-19-6 AZ084/CAS No.929300-19-6 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer. price>
R-R-4165 BX471 hydrochloride CAS No.288262-96-4 BX471 hydrochloride (ZK-811752 hydrochloride)/CAS No.288262-96-4 is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. price>
R-R-4166 R243 CAS No.688352-84-3 R243/CAS No.688352-84-3 is a potent and selective CCR8 antagonist. R243 inhibits CCL1/CCR8 interaction and inhibits CCR8 signaling and chemotaxis. R243 has antinociceptive and anti-inflammatory effects. price>
R-R-4167 GW 766994 CAS No.408303-43-5 GW 766994 (GW 994)/CAS No.408303-43-5 is a chemokine receptor-3 (CCR3) antagonist that is orally active and specific. GW 766994 has the potential for research into asthma and eosinophilic bronchitis. price>