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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4155 (1S)-CCR2 antagonist 1 CAS No.1683534-97-5 (1S)-CCR2 antagonist 1/CAS No.1683534-97-5 is a left-handed chiral body of CCR2 antagonist 1 (HY-112792). CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM. price>
R-R-4156 RS102895 hydrochloride CAS No.1173022-16-6 RS102895 hydrochloride/CAS No.1173022-16-6 is a potent CCR2 antagonist, with an IC50 of 360 nM, and shows no effect on CCR1. price>
R-R-4157 Cenicriviroc CAS No.497223-25-3 Cenicriviroc (TAK-652)/CAS No.497223-25-3 is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity. price>
R-R-4158 TAK-779 CAS No.229005-80-5 TAK-779/CAS No.229005-80-5 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells. price>
R-R-4159 Zelnecirnon CAS No.2366152-15-8 Zelnecirnon (RPT193)/CAS No.2366152-15-8 is an orally active inhibitor of CCR4, blocks the recruitment of Th2 inflammatory immune cells into inflamed tissues. Zelnecirnon can be used for allergic inflammation in atopic dermatitis, asthma, and other diseases research. price>
R-R-4160 CCR6 antagonist 1 CAS No.588674-64-0 CCR6 antagonist 1/CAS No.588674-64-0 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs). price>
R-R-4161 CCR6 inhibitor 1 CAS No.2437547-04-9 CCR6 inhibitor 1/CAS No.2437547-04-9 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer. price>
R-R-4162 AZD2098 CAS No.566203-88-1 AZD2098/CAS No.566203-88-1 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research. price>
R-R-4163 ZK756326 dihydrochloride CAS No.1780259-94-0 ZK756326 dihydrochloride/CAS No.1780259-94-0 is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8. price>
R-R-4164 AZ084 CAS No.929300-19-6 AZ084/CAS No.929300-19-6 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer. price>