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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4136 ZCZ011 CAS No.1998197-39-9 ZCZ011/CAS No.1998197-39-9 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain. price>
R-R-4137 AEF0117 CAS No.1610878-71-1 AEF0117/CAS No.1610878-71-1 is a signaling-specific inhibitor of the cannabinoid receptor 1 (CB1-SSi). AEF0117 plays an important role in Cannabis use disorder (CUD). price>
R-C-2438 Imidafenacin CAS:170105-16-5 Imidafenacin(KRP-197,ONO-8025)is a urinary antispasmodic of the anticholinergic class.Imidafenacin(KRP-197;ONO-8025)is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM;less potent for M2 receptors(IC50=4.13nM).IC50 value:0.3nM(M3). price>
R-R-4138 CB2 receptor agonist 2 CAS No.1314230-75-5 CB2 receptor agonist 2/CAS No.1314230-75-5 is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor with a Ki of 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2. price>
R-R-4139 PSB-SB-487 CAS No.1399049-81-0 PSB-SB-487/CAS No.1399049-81-0 is a potent GPR55 antagonist and CB2 agonist with an IC50 value of 0.113 µM for GPR55, and a Ki value of 0.292 µM for human CB2. PSB-SB-487 can be used for researching diabetes, Parkinson’s disease, neuropathic pain, and cancer. price>
R-R-4140 CB2 receptor agonist 3 CAS No.919077-81-9 CB2 receptor agonist 3/CAS No.919077-81-9 is a robust and selective CB2 cannabinoid agonist with Kis of 7.6 and 900 nM for CB2 and CB1, respectively. CB2 receptor agonist 3 significantly increases P-ERK 1/2 expression in HL-60 cells. price>
R-R-4141 (Rac)-Zevaquenabant CAS No.1610420-28-4 (Rac)-Zevaquenabant ((Rac)-MRI-1867/CAS No.1610420-28-4, compound 6b) is a cannabinoid receptor type 1 (CB1R)/iNOS antagonist, with a Ki of 5.7 nM for CB1R. (Rac)-Zevaquenabant is potential for the research of liver fibrosis. price>
R-R-4142 N-Arachidonyldopamine CAS No.199875-69-9 N-Arachidonyldopamine/CAS No.199875-69-9 is a potent and selective endogenous CB1 receptor agonist with a Ki of 250 nM. N-Arachidonyldopamine is also a potent and selective TRPV1 agonist an with EC50 of ~ 50 nM. price>
R-R-4143 CB2R/FAAH modulator-2 CAS No.2876918-68-0 CB2R/FAAH modulator-2 (compound 26)/CAS No.2876918-68-0 is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-2 are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection. price>
R-R-4144 CB1R antagonist 1 CAS No.334668-69-8 CB1R Allosteric modulator 5/CAS No.334668-69-8, a selective cannabinoid-1 receptor (CB1R) inverse agonist with an IC50 value of 4.2 μM and EC50 value of ＞10 μM. CB1R Allosteric modulator 5 can be used for the research of metabolic and obesity. price>