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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4145 BMS-646256 CAS No.464213-10-3 BMS-646256/Ibipinabant/SLV319/CAS No.464213-10-3 is a potent, selective and orally active antagonist of cannabinoid CB1 receptor, with a Ki of 7.8 nM. Ibipinabant shows more than 1000-fold selectivity for CB1 over CB2 (Ki=7943 nM). Ibipinabant can be used for the research of obesity and diabetic. price>
R-R-4146 NIDA-41020 CAS No.502486-89-7 NIDA-41020/CAS No.502486-89-7 is a potent and selective cannabinoid receptor 1(CB1) antagonist with a Ki of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET). price>
R-R-4147 MJ15 CAS No.944154-76-1 MJ15/CAS No.944154-76-1 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice. price>
R-R-4148 GAT228 CAS No.1446648-15-2 GAT228/CAS No.1446648-15-2, the enantiomer of GAT211, is an allosteric cannabinoid receptor 1 (CB1) ligand. price>
R-R-4149 Pregnenolone (Standard) CAS No.145-13-1 Pregnenolone (Standard)/CAS No.145-13-1 is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels. price>
R-R-4150 N-Arachidonyldopamine-d8 CAS No.1159908-42-5 N-Arachidonyldopamine-d8/CAS No.1159908-42-5 is the deuterium labeled N-Arachidonyldopamine. price>
R-R-4151 RS 504393 CAS No.300816-15-3 RS 504393/CAS No.300816-15-3 is a selective CCR2 chemokine receptor antagonist (IC50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively). price>
R-R-4152 Bindarit CAS No.130641-38-2 Bindarit (AF2838)/CAS No.130641-38-2 is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity. price>
R-R-4153 INCB3344 CAS No.1262238-11-8 INCB3344/CAS No.1262238-11-8 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity. price>
R-R-4154 Ilacirnon CAS No.1100318-47-5 CCX140 (CCX140-B)/CAS No.1100318-47-5 is a potent CCR2 antagonist. price>