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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4177 BI-6901 CAS No.2040401-92-9 BI 6901/CAS No.2040401-92-9 is a potent, selective CCR10 antagonist (pIC50=9.0). BI 6901 shows high selectivity over other GPCRs, including a number of other chemokine receptors. BI 6901 is efficacious in the murine DNFB model of contact hypersensitivity and can be used for inflammation research. price>
R-R-4178 INCB 3284 CAS No.887401-92-5 INCB 3284/CAS No.887401-92-5 is a potent, selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2, with an IC50 of 3.7 nM. INCB 3284 can be used in the research of acute liver failure. price>
R-R-4179 MK-0812 Succinate CAS No.851916-42-2 MK-0812 Succinate/CAS No.851916-42-2 is a potent and selective CCR2 antagonist with high affinity at CCR2. price>
R-R-4180 SB-328437 CAS No.247580-43-4 SB-328437/CAS No.247580-43-4 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. price>
R-R-4181 ML604086 CAS No.850330-18-6 ML604086/CAS No.850330-18-6 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations. price>
R-R-4182 ALK4290 CAS No.1251528-23-0 ALK4290 (AKST4290)/CAS No.1251528-23-0 is a potent and orally active CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3.2 nM for hCCR3. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism. price>
R-R-4183 PF-07054894 CAS No.2413693-96-4 PF-07054894/CAS No.2413693-96-4 is a potent CCR6 antagonist. PF-07054894 targets G protein-coupled receptor (GPCR). PF-07054894 can be used in research of inflammatory bowel disease. price>
R-R-4184 BMS CCR2 22 CAS No.445479-97-0 BMS CCR2 22/CAS No.445479-97-0 is a potent, specific and high affinity CC-type chemokine receptor 2 (CCR2) antagonist with excellent binding affinity (binding IC50 of 5.1 nM) and potent functional antagonism (calcium flux IC50 of 18 nM and chemotaxis IC50 of 1 nM). price>
R-R-4185 CCR2 antagonist 1 CAS No.1683534-96-4 CCR2 antagonist 1/CAS No.1683534-96-4 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM. price>
R-R-4186 SB297006 CAS No.58816-69-6 SB297006/CAS No.58816-69-6 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells. price>