Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-R-2705	(E/Z)-SIB-1893 CAS No.6266-99-5	(E/Z)-SIB-1893/CAS No.6266-99-5 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist.	price>
R-R-2706	VU-29 CAS No.890764-36-0	VU-29/CAS No.890764-36-0 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor (EC50=9 nM and Ki=244 nM for rmGluR5). VU-29 is selective for mGluR5 relative to other mGluR subtypes (EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM).	price>
R-R-2707	(RS)-APICA CAS No.170847-18-4	(RS)-APICA/CAS No.170847-18-4 is a selective group II metabotropic glutamate receptor (mGluR II) antagonist. (RS)-APICA shows potential neuroprotective effect.	price>
R-R-2708	Biphenylindanone A CAS No.866823-73-6	Biphenylindanone A (BINA)/CAS No.866823-73-6 is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders.	price>
R-R-2709	ABP688 CAS No.924298-51-1	ABP688/CAS No.924298-51-1 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor.	price>
R-R-2710	FITM CAS No.932737-65-0	FITM/CAS No.932737-65-0 is a negative allosteric modulator of mGlu1 receptor with a Ki of 2.5 nM.	price>
R-R-2711	LY456236 CAS No.338736-46-2	LY456236/CAS No.338736-46-2 is a selective, non-competitive and orally active mGlu1 receptor antagonist that inhibits phosphoinositide hydrolysis with an IC50 of 0.145 μM. LY456236 also inhibits EGFR with an IC50 of 0.91 μM.	price>
R-R-2712	Methoxy-PEPy CAS No.524924-76-3	Methoxy-PEPy/CAS No.524924-76-3 is a potent and highly selective mGlu5 receptor antagonist with IC50 of 1 nM.	price>
R-R-2713	Pomaglumetad methionil hydrochloride CAS No.635318-26-2	Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride)/CAS No.635318-26-2 is an orally active, methionine prodrug of the selective mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil hydrochloride has the potential for schizophrenia research.	price>
R-R-2714	HTL14242 CAS No.1644645-32-8	HTL14242 (HTL0014242)/CAS No.1644645-32-8 is an advanced and orally active mGlu5 NAM with a pKi and a pIC50 of 9.3 and 9.2, respectively.	price>

...

163