Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4738	Sodium Camptothecin CAS No.25387-67-1	Sodium Camptothecin/CAS No.25387-67-1 is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.	price>
R-R-4739	2-(Methylamino)-1H-purin-6(7H)-one CAS No.10030-78-1	2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine)/CAS No.10030-78-1 is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids.	price>
R-R-4740	Thymidine-d4 CAS No.347841-67-2	Thymidine-d4/CAS No.347841-67-2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.	price>
R-R-4741	Sterigmatocystine CAS No.10048-13-2	Sterigmatocystine/CAS No.10048-13-2 is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals.	price>
R-R-4742	DHPS-IN-1 CAS No.2643300-54-1	DHPS-IN-1/CAS No.2643300-54-1, with the best DHPS inhibitory potency (IC50 = 0.014 μM), exhibits excellent inhibition against melanoma cells.	price>
R-R-4743	Filibuvir CAS No.877130-28-4	Filibuvir/CAS No.877130-28-4 is an orally active, selective non-nucleoside inhibitor of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase (RdRp). Filibuvir binds noncovalently in the thumb II allosteric pocket of NS5B. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM for both isoforms, respectively. Filibuvir preferentially inhibits elongative RNA synthesis and potently decreases viral RNA accumulation.	price>
R-R-4744	SMN-C2 CAS No.1446311-56-3	SMN-C2/CAS No.1446311-56-3, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex. SMN-C2 can be used in spinal muscular atrophy (SMA) research.	price>
R-R-4745	Laflunimus CAS No.147076-36-6	Laflunimus (HR325)/CAS No.147076-36-6 is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor.	price>
R-R-4746	Adenine-d CAS No.109923-52-6	Adenine-d/CAS No.109923-52-6 is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.	price>
R-R-4747	MMV688845 CAS No.2208962-35-8	MMV688845/CAS No.2208962-35-8 is a nontuberculous mycobacteria (NTM) RNA polymerase inhibitor with bactericidal activity against Mycobacterium abscessus and anti-tuberculosis efficacy.	price>

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