Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4690	6-Hydroxy-DOPA CAS No.21373-30-8	6-Hydroxy-DOPA/CAS No.21373-30-8 is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer.	price>
R-R-4691	5-Propargylamino-dCTP CAS No.115899-39-3	5-Propargylamino-dCTP/CAS No.115899-39-3 is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-4706	Brr2-IN-3 CAS No.2104030-82-0	Brr2-IN-3/CAS No.2104030-82-0 is a potent and selective Brr2 helicase allosteric Inhibitor. Brr2-IN-3 inhibits helicase activity in dose-dependent manner with an IC50 value of 1.3 μM.	price>
R-R-4707	UNC9512 CAS No.3032393-24-8	UNC9512/CAS No.3032393-24-8 is a potent methyl-lysine reader p53 binding protein 1 (53BP1) antagonist. UNC9512 can be used to study the role of 53BP1 in DNA repair, gene editing and tumorigenesis.	price>
R-R-4708	CeMMEC13 CAS No.1790895-25-8	CeMMEC13/CAS No.1790895-25-8 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.	price>
R-R-4709	Antipain dihydrochloride CAS No.37682-72-7	Antipain dihydrochloride/CAS No.37682-72-7 is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice.	price>
R-R-4710	CM03 CAS No.2101208-44-8	CM03/CAS No.2101208-44-8 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells.	price>
R-R-4711	NSAH CAS No.1099592-35-4	NSAH/CAS No.1099592-35-4 is a reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.	price>
R-R-4712	Sorivudine CAS No.77181-69-2	Sorivudine (BV-araU)/CAS No.77181-69-2 is an orally active synthetic pyrimidine nucleoside antimetabolite agent. Sorivudine derives its antiviral activity from selective conversion by a specific thymidine kinase present in certain DNA viruses to nucleotides, which can in turn interfere with viral DNA synthesis.	price>
R-R-4713	N-Nitrosodiethylamine-d10 CAS No.1219794-54-3	N-Nitrosodiethylamine-d10/CAS No.1219794-54-3 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.	price>

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