Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4691	5-Propargylamino-dCTP CAS No.115899-39-3	5-Propargylamino-dCTP/CAS No.115899-39-3 is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-4706	Brr2-IN-3 CAS No.2104030-82-0	Brr2-IN-3/CAS No.2104030-82-0 is a potent and selective Brr2 helicase allosteric Inhibitor. Brr2-IN-3 inhibits helicase activity in dose-dependent manner with an IC50 value of 1.3 μM.	price>
R-R-4707	UNC9512 CAS No.3032393-24-8	UNC9512/CAS No.3032393-24-8 is a potent methyl-lysine reader p53 binding protein 1 (53BP1) antagonist. UNC9512 can be used to study the role of 53BP1 in DNA repair, gene editing and tumorigenesis.	price>
R-R-4708	CeMMEC13 CAS No.1790895-25-8	CeMMEC13/CAS No.1790895-25-8 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.	price>
R-R-4709	Antipain dihydrochloride CAS No.37682-72-7	Antipain dihydrochloride/CAS No.37682-72-7 is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice.	price>
R-R-4710	CM03 CAS No.2101208-44-8	CM03/CAS No.2101208-44-8 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells.	price>
R-R-4711	NSAH CAS No.1099592-35-4	NSAH/CAS No.1099592-35-4 is a reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.	price>
R-R-4712	Sorivudine CAS No.77181-69-2	Sorivudine (BV-araU)/CAS No.77181-69-2 is an orally active synthetic pyrimidine nucleoside antimetabolite agent. Sorivudine derives its antiviral activity from selective conversion by a specific thymidine kinase present in certain DNA viruses to nucleotides, which can in turn interfere with viral DNA synthesis.	price>
R-R-4713	N-Nitrosodiethylamine-d10 CAS No.1219794-54-3	N-Nitrosodiethylamine-d10/CAS No.1219794-54-3 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.	price>
R-R-4714	Nogalamycin CAS No.1404-15-5	Nogalamycin/CAS No.1404-15-5 is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer.	price>

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