Product apis-dna-damage-dna-repa

Home > products > apis> dna-damage-dna-repa

Catalog	name	Description	price
R-R-4681	N-Acetyl-Calicheamicin CAS No.108212-76-6	N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ)/CAS No.108212-76-6, an enediyne anti-tumor antibiotic, is an ADC cytotoxin. N-Acetyl-Calicheamicin can induce DNA damage, and can be used in the synthesis of ADC.	price>
R-R-4682	Garenoxacin Mesylate hydrate CAS No.223652-90-2	Garenoxacin (BMS284756) Mesylate hydrate/CAS No.223652-90-2 is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms.	price>
R-R-4683	Netropsin dihydrochloride CAS No.18133-22-7	Netropsin dihydrochloride/CAS No.18133-22-7 is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride exhibits antiviral activity against the vaccinia virus.	price>
R-R-4684	Adenine-13C CAS No.86967-48-8	Adenine-13C/CAS No.86967-48-8 is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.	price>
R-R-4685	Tezacitabine CAS No.130306-02-4	Tezacitabine/CAS No.130306-02-4 is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue. Tezacitabine irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine effectively induces cells apoptotic. Tezacitabine has the potential for leukemias and solid tumors (carcinomas) treatment.	price>
R-C-3016	NU7441 (KU-57788) CAS：503468-95-9	NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits mTOR and PI3K with IC50 of 1.7 μM and 5 μM in cell-free assays, respectively. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.Only for scientific research, not for human body.	price>
R-R-4686	AV-153 free base CAS No.19350-66-4	AV-153 free base/CAS No.19350-66-4, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity.	price>
R-R-4687	DTP3 TFA CAS No.2759216-46-9	DTP3 TFA/CAS No.2759216-46-9 is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway.	price>
R-R-4688	H3B-968 CAS No.2912294-90-5	H3B-968/CAS No.2912294-90-5 is a potent inhibitor of Werner syndrome protein (WRN) (IC50=~10 nM)，which acts function as helicase，ATPase，and exonuclease. WRN exhibits synthetic lethal activity in cancer research. However，H3B-968 inhibits WRN helicase activity，competitively with ATP.	price>
R-R-4689	Pseudouridimycin CAS No.1566586-52-4	Pseudouridimycin (PUM)/CAS No.1566586-52-4, an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria.	price>

...