Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4714	Nogalamycin CAS No.1404-15-5	Nogalamycin/CAS No.1404-15-5 is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer.	price>
R-R-4715	hDHODH-IN-4 CAS No.1644156-56-8	hDHODH-IN-4/CAS No.1644156-56-8 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8.	price>
R-R-4716	5-Methoxyflavone CAS No.42079-78-7	5-Methoxyflavone/CAS No.42079-78-7, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors.	price>
R-R-4717	WRN inhibitor 4 CAS No.2923009-45-2	WRN inhibitor 4 (example 107)/CAS No.2923009-45-2, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 4 can be used for the research of cancer.	price>
R-R-4718	POL1-IN-1 CAS No.1822358-25-7	POL1-IN-1/CAS No.1822358-25-7 is a RNA polymerase 1 (POL1, also known as Pol I) inhibitor with an IC50 of less than 0.5 uM. POL1-IN-1 inhibits ribosome biogenesis by inhibiting POL1 transcription.	price>
R-R-4719	ML372 CAS No.1331745-61-9	ML372/CAS No.1331745-61-9 inhibits survival motor neuron (SMN) protein ubiquitination, increases SMN protein stability without affecting mRNA expression. ML372 improves spinal muscular atrophy (SMA) in mice. ML372 is brain penetrant and has a reasonable exposure and half-life in vivo.	price>
R-R-4720	RNase L-IN-1	RNase L-IN-1 (compound 17a) is an inhibitor of RNase L, or Ribonuclease L. RNase L degrades RNAs to prevent viral replication, and mediates the innate immune responses and inflammation.	price>
R-R-4721	Cytarabine triphosphate trisodium CAS No.1179343-17-9	Cytarabine triphosphate (Ara-CTP) trisodiu/CAS No.1179343-17-9, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine.	price>
R-C-3061	BRD3308 CAS:1550053-02-5	BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM.	price>
R-R-4737	HBV-IN-4 CAS No.2305897-84-9	HBV-IN-4/CAS No.2305897-84-9, a phthalazinone derivative, is a potent and orally active HBV DNA replication inhibitor with an IC50 of 14 nM. HBV-IN-4 induces the formation of genome-free capsids and has potent anti-HBV potencies.	price>

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