Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4758	FAICAR CAS No.13018-54-7	FAICAR (5-Formamidoimidazole-4-carboxamide ribotide)/CAS No.13018-54-7 is a purine nucleotide.	price>
R-R-4759	Cytarabine-d2 CAS No.40632-26-6	Cytarabine-d2/CAS No.40632-26-6 is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV.	price>
R-R-4760	ddTTP trisodium	ddTTP trisodium is one of 2,3-dideoxyribonucleoside 5-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing.	price>
R-R-4761	WRN inhibitor 1 CAS No.2923008-44-8	WRN inhibitor 1 (example 7)/CAS No.2923008-44-8 is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor that inhibits WRN helicase domain activity. WRN inhibitor 1 has the potential to study cancer.	price>
R-R-4762	Remdesivir-d5	Remdesivir-d5 is a deuterium labeled Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of 2019-nCoV (COVID-19) infection in vitro.	price>
R-R-4763	H3B-8800 CAS No.1825302-42-8	H3B-8800/CAS No.1825302-42-8 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant.	price>
R-R-4764	Setrobuvir CAS No.1071517-39-9	Setrobuvir (ANA598)/CAS No.1071517-39-9 is an orally active non-nucleosidic HCV NS5B polymerase inhibitor. ANA-598 inhibits both de novo RNA synthesis and primer extension, with IC50s between 4 and 5 nM. Setrobuvir also shows excellent binding affinity to SARS-CoV-2 RdRp and induces RdRp inhibition.	price>
R-R-4765	Methotrexate-d3 CAS No.432545-63-6	Methotrexate-d3 (Amethopterin-d3)/CAS No.432545-63-6 is the deuterium labeled Methotrexate. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).	price>
R-R-4766	7-Iodo-2,3-dideoxy-7-deaza-guanosine CAS No.114748-67-3	7-Iodo-2,3-dideoxy-7-deaza-guanosine/CAS No.114748-67-3 is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions.	price>
R-R-4767	DNA31 CAS No.845626-57-5	DNA31/CAS No.845626-57-5 is a potent RNA polymerase inhibitor.	price>

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