Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4561	Biotin-16-dUTP trisodium	Biotin-16- dUTP (Biotin-16-deoxyuridine-5-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications.	price>
R-R-4563	Br-DAPI CAS No.2387906-44-5	Br-DAPI/CAS No.2387906-44-5 is a marker dye in DAPI series. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells. Storage: Keep away from light.	price>
R-R-4565	3,6-Dichlorotrimellitic acid CAS No.137071-78-4	3,6-Dichlorotrimellitic acid/CAS No.137071-78-4 is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.	price>
R-R-4566	Nedisertib CAS No.1637542-33-6	Nedisertib (M3814)/CAS No.1637542-33-6 is a potent orally available selective DNA-PK inhibitor, with an IC50 of <3 nM. Anti-tumor activity.	price>
R-R-4567	VX-984 CAS No.1476074-39-1	VX-984/CAS No.1476074-39-1 is an orally active, potent, selective and BBB-penetrated DNA-PK inhibitor. VX-984 efficiently inhibits NHEJ (non-homologous end joining) and increases DSBs (DNA double-strand breaks). VX-984 can be used for glioblastomas (GBM) and non-small cell lung cancer (NSCLC) research. VX-984 is a de novo deuterium.	price>
R-R-4568	CC-115 CAS No.1228013-15-7	CC-115/CAS No.1228013-15-7 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling.	price>
R-R-4569	BAY-8400 CAS No.2763602-59-9	BAY-8400/CAS No.2763602-59-9 is an orally active, potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (IC50=81 nM). BAY-8400 can be used for the research of cancer.	price>
R-R-4570	CC-115 hydrochloride CAS No.1300118-55-1	CC-115 hydrochloride/CAS No.1300118-55-1 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling.	price>
R-R-4571	(R)-VX-984 CAS No.2448475-19-0	(R)-VX-984/(R)-M9831/CAS No.2448475-19-0 is the (R)-enantiomer of VX-984. VX-984 is a potent DNA-PK inhibitor.	price>
R-R-4572	VVD-214 CAS No.3026500-20-6	VVD-214/RO7589831/VVD-133214/CAS No.3026500-20-6 is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity. VVD-214 is potent in causing double-stranded DNA breaks, nuclear swelling, and cell death in high microsatellite instability (MSI) cancers.	price>

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