Catalog |
name |
Description |
price |
R-R-4540 |
2-Iodoacetamide-d4 CAS No.1219802-64-8 |
2-Iodoacetamide-d4/CAS No.1219802-64-8 is the deuterium labeled 2-Iodoacetamide. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics. |
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R-R-4541 |
Miriplatin CAS No.141977-79-9 |
Miriplatin (SM-11355)/CAS No.141977-79-9 is a chemotherapy agent which belongs to the class of alkylating agents. |
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R-R-4542 |
Tesirine intermediate-1 CAS No.1430738-05-8 |
Tesirine intermediate-1/CAS No.1430738-05-8 is the intermediate of Tesirine (HY-128952). Tesirine (SG3249), a pyrrole benzodiazepine (PBD) dimer, is a DNA small channel crosslinker with strong cytotoxicity. Tesirine can be used to synthesize Antibody-Drug Conjugates (ADCs), the warhead component of the payload is SG3199 (HY-101161), which has strong anticancer cell activity. |
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R-R-4543 |
(S)-Seco-Duocarmycin SA CAS No.152785-82-5 |
(S)-Seco-Duocarmycin SA/CAS No.152785-82-5 is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates. |
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R-R-4544 |
Duocarmycin Analog CAS No.372954-15-9 |
Duocarmycin Analog/CAS No.372954-15-9 is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin. |
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R-R-4545 |
Temozolomide-d3 CAS No.208107-14-6 |
Temozolomide-d3/CAS No.208107-14-6 is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects. |
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R-R-4546 |
Cyclophosphamide-d4 CAS No.173547-45-0 |
Cyclophosphamide-d4/CAS No.173547-45-0 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. |
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R-R-4547 |
Carboplatin-d4 |
Carboplatin-d4 is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent. |
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R-R-4548 |
Carmustine-d8 |
Carmustine-d8 is the deuterium labeled Carmustine. Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA. |
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R-R-4549 |
NCI172112 CAS No.56605-16-4 |
NCI172112/CAS No.56605-16-4 is a classical bifunctional alkylating agent synthesized in an effort to develop antitumor agents effective against CNS tumors. |
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