Product apis-dna-damage-dna-repa

Home > products > apis> dna-damage-dna-repa

Catalog	name	Description	price
R-C-513	CP466722 cas：1080622-86-1	CP-466722 is a rapidly reversible inhibitor of ATM,with an IC50 of 4.1 μM,and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members.	price>
R-C-518	HQL-79 cas:162641-16-9	HQL-79 is a selective inhibitor of hematopoietic prostaglandin D (PGD) synthase, that structurally is a synthetic tetrazole compound originally prepared as a possible antihistamine.	price>
R-C-565	ACY-1215 cas:1316214-52-4	Ricolinostat (ACY-1215,Rocilinostat)is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay.It is>10-fold more selective for HDAC6 than HDAC1/2/3(class I HDACs)with slight activity against HDAC8,minimal activity against HDAC4/5/7/9/11,Sirtuin1,and Sirtuin2.Ricolinostat (ACY-1215)suppresses cell proliferation and promotes apoptosis.	price>
R-C-587	Amrubicin cas:110267-81-7	Amrubicin is a synthetic anthracycline antibiotic.It inhibits DNA topoisomerase II. Antineoplastic.	price>
R-C-602	CGK733 cas:905973-89-9	CGK733,a thiourea-containing compound,was originally identified as a specific inhibitor of ATR and ATM kinases (IC50=~200 nM).In prematurely senescent breast, lung, and colon cancer cells CGK733 reportedly suppresses ATM-mediated p21 expression required for survival,resulting in cell death.	price>
R-C-627	RI-1 (RAD51 inhibitor) cas:415713-60-9	RI-1 is a small molecule that inhibits the central recombination protein RAD51. RI-1 specifically reduces gene conversion in human cells while stimulating single strand annealing.RI-1 binds covalently to the surface of RAD51 protein at cysteine 319 that likely destabilizes an interface used by RAD51 monomers to oligomerize into filaments on DNA.	price>
R-C-637	PENTOSTATIN cas:53910-25-1	Pentostatin is a potent inhibitor of adenosine deaminase.The drug is effective in the treatment of many lymphoproliferative malignancies,particularly hairy-cell leukemia.It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.	price>
R-C-661	SB1317 cas:937270-47-8	SB1317 is a potent inhibitor of CDK2,JAK2,and FLT3 for the treatment of cancer, with IC50 of 13,73,and 56 nM for CDK2,JAK2 and FLT3,respectively.	price>
R-C-669	BAY57-1293 cas:348086-71-5	Pritelivir(AIC316),an inhibitor of the viral helicase-primase complex,exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection.Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2)with the IC50 of 0.02 μM against HSV1-2.	price>
R-C-721	Tenovin-3 CAS:1011301-27-1	Tenovin-3 is a small molecule activator of p53 transcriptional activity. It increases p53 activity in MCF-7 cells when used at a concentration of 10 µM.It also increases the level of K40-acetylated alpha-tubulin in H1299 cells and inhibits SIRT2 protein deacetylase activity.	price>

...