Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-C-2668	AG-14361 CAS:328543-09-5	AG14361 is a potent PARP-1 inhibitor,with a Ki of < 5nM,and in permeabilized SW620 and intact SW620 cells,the IC50s are 29nM and 14nM,respectively.	price>
R-C-2688	TCS HDAC6 20b CAS：956154-63-5	TCS HDAC6 20b,selective inhibitor of histone deacetylase 6(HDAC6).Inhibits HCT116 growth in combination with taxol. Also inhibits growth of MCF-7 cells stimulated by estrogen.	price>
R-C-2669	Viomycin CAS:32988-50-4	Viomycin(free base)is a tuberactinomycin antibiotic essential for treating multidrug-resistant tuberculosis.It inhibits bacterial protein synthesis by blocking elongation factor G(EF-G)catalyzed translocation of messenger RNA on the ribosome.	price>
R-C-2670	NSC 3852 CAS:3565-26-2	NSC 3852 is an HDAC(histone deacetylase)inhibitor.	price>
R-C-2672	Flumequine CAS:42835-25-6	Flumequine(R-802)is a quinolone antibiotic,and acts as a topoisomerase II inhibitor,with an IC50 of 15μM(3.92μg/mL).	price>
R-C-2675	Ellipticine CAS：519-23-3	Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor.	price>
R-C-2676	Costunolide CAS：553-21-9	Costunolide(NSC 106404),a natural sesquiterpene compound with multiple biological activities;inhibits FPTase with IC50 of 20μM,also inhibits telomerase with IC50 of 65-90μM.	price>
R-C-2677	KU 55933 CAS：587871-26-9	KU-55933 is an ATM inhibitor,which blocks the phosphorylation of Akt induced by insulin and insulin-like growth factor I in cancer cells that exhibit abnormal Akt activity. Moreover,KU-55933 inhibits cancer cell proliferation by inducing G(1)cell cycle arrest.It does so through the downregulation of the synthesis of cyclin D1,a protein known to be elevated in a variety of tumors.	price>
R-C-2679	Carmofur CAS：61422-45-5	Carmofur(HCFU),a derivative of 5-Fluorouracil,is an antineoplastic agent.Carmofur is an inhibitor of acid ceramidase with an IC50 of 79nM for the rat enzyme.Carmofur inhibits the SARS-CoV-2 main protease(Mpro).Carmofur Inhibits SARS-CoV-2 in Vero E6 cell with an EC50 of 24.3μM.	price>
R-C-2680	Altretamine CAS：645-05-6	Altretamine is classified as an alkylating antineoplastic agent.This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde,a product of CYP450-mediated N-demethylation.	price>

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