Product apis-cytoskeletal-signaling

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Catalog	name	Description	price
R-R-0308	Pentixafor CAS: 1341207-62-2	Pentixafor is a medicinal compound that has been developed as an anticancer agent. This compound is an analog of the CXCR4 receptor inhibitor, which is found in human urine and Chinese medicinal herbs. Pentixafor works by inhibiting kinases that are involved in cancer cell growth and survival, leading to apoptosis or programmed cell death. It specifically targets tumor cells and prevents them from spreading to other parts of the body. Pentixafor has shown promising results in preclinical studies for the treatment of various types of cancer, including breast, prostate, and lung cancer. Its ability to selectively target cancer cells makes it a potential breakthrough in cancer treatment research.	price>
R-C-463	KW-2478 cas:819812-04-9	KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.	price>
R-C-563	PF8380 cas:1144035-53-9	Pf-8380 is an effective automatic classification inhibitor with IC (50) of 2.8 nm in isolated enzyme assay and 101 nm in human blood.	price>
R-C-671	STA9090(Ganetespib) cas:888216-25-9	Ganetespib is a heat shock protein 90(HSP90)inhibitor which exhibits potent cytotoxicity in a wide variety of hematological and solid tumor cell lines.	price>
R-C-758	Romidepsin (FK228, Depsipeptide) cas:128517-07-7	Romidepsin(FK 228)is a Histone deacetylase(HDAC)inhibitor with anti-tumor activities.Romidepsin(FK 228)inhibits HDAC1,HDAC2,HDAC4,and HDAC6 with IC50s of 36 nM,47 nM,510 nM and 1.4 μM,respectively.Romidepsin(FK 228)is produced by Chromobacterium violaceum,induces cell G2/M phase arrest and apoptosis.	price>
R-C-1010	CH5138303 cas:959763-06-5	CH5138303 is a triazine Hsp90 inhibitor.1 CH5138303 binds to the N-terminus of Hsp90α(Kd=0.52 nM)and inhibits growth of HCT116 and NCI-N87 human tumor cell lines in vitro(IC50s=89 and 66 nM,respectively).CH5138303 also inhibits growth of human NCI-N87 gastric cancer xenografts(ED50=3.9 mg/kg)and displays high oral bioavailability in mice.	price>
R-C-1032	epothilone A CAS No. 152044-53-6	Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition,leading to cytotoxicity.	price>
R-C-1058	INH1 CAS:313553-47-8	INH1 specifically disrupts the Hec1/Nek2 interaction via direct Hec1 binding. INH1 shows promising cancer inhibition activity both in vitro and in vivo.	price>
R-C-1059	INH6 CAS：1001753-24-7	INH6 is a potent Hec1 inhibitor,which specifically disrupts the Hec1/Nek2 interaction and causes chromosome mis-alignment.	price>
R-C-1060	E7010(ABT-751) CAS：141430-65-1	ABT-751(E7010)binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules,not a substrate for the MDR transporter and is active against cell lines resistant to vincristine,doxorubicin,and cisplatin.	price>

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