Catalog name Description price
R-C-463 KW-2478 cas:819812-04-9 KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM. price>
R-C-563 PF8380 cas:1144035-53-9 Pf-8380 is an effective automatic classification inhibitor with IC (50) of 2.8 nm in isolated enzyme assay and 101 nm in human blood. price>
R-C-671 STA9090(Ganetespib) cas:888216-25-9 Ganetespib is a heat shock protein 90(HSP90)inhibitor which exhibits potent cytotoxicity in a wide variety of hematological and solid tumor cell lines. price>
R-C-758 Romidepsin (FK228, Depsipeptide) cas:128517-07-7 Romidepsin(FK 228)is a Histone deacetylase(HDAC)inhibitor with anti-tumor activities.Romidepsin(FK 228)inhibits HDAC1,HDAC2,HDAC4,and HDAC6 with IC50s of 36 nM,47 nM,510 nM and 1.4 μM,respectively.Romidepsin(FK 228)is produced by Chromobacterium violaceum,induces cell G2/M phase arrest and apoptosis. price>
R-C-1010 CH5138303 cas:959763-06-5 CH5138303 is a triazine Hsp90 inhibitor.1 CH5138303 binds to the N-terminus of Hsp90α(Kd=0.52 nM)and inhibits growth of HCT116 and NCI-N87 human tumor cell lines in vitro(IC50s=89 and 66 nM,respectively).CH5138303 also inhibits growth of human NCI-N87 gastric cancer xenografts(ED50=3.9 mg/kg)and displays high oral bioavailability in mice. price>
R-C-1032 epothilone A CAS No. 152044-53-6 Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition,leading to cytotoxicity. price>
R-C-1058 INH1 CAS:313553-47-8 INH1 specifically disrupts the Hec1/Nek2 interaction via direct Hec1 binding. INH1 shows promising cancer inhibition activity both in vitro and in vivo. price>
R-C-1059 INH6 CAS:1001753-24-7 INH6 is a potent Hec1 inhibitor,which specifically disrupts the Hec1/Nek2 interaction and causes chromosome mis-alignment. price>
R-C-1060 E7010(ABT-751) CAS:141430-65-1 ABT-751(E7010)binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules,not a substrate for the MDR transporter and is active against cell lines resistant to vincristine,doxorubicin,and cisplatin. price>
R-C-1168 Elesclomol (STA-4783) CAS: 488832-69-5 Elesclomol(STA-4783)is an oxidative stress inducer that induces cancer cell apoptosis.Elesclomol is a reactive oxygen species(ROS)inducer.Elesclomol shows antitumor activity against a broad range of cancer cell types.Elesclomol is also a highly lipophilic Cu2+-binding molecule.Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research. price>