Product apis-cell-cycle

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Catalog	name	Description	price
R-C-558	GW7647 cas:265129-71-3	GW7647 is a potent PPARαagonist,with EC50s of 6 nM,1.1μM,and 6.2μM for human PPARα,PPARγ and PPARδ,respectively.	price>
R-C-567	sch900776 cas:891494-63-6	SCH900776(MK-8776) is a potent,selective and orally bioavailable inhibitor of checkpoint kinase1(Chk1) with an IC50 of 3 nM.SCH900776 shows 50-and 500-fold selectivity over CDK2 and Chk2,respectively.	price>
R-C-605	Belinostat cas:414864-00-9	Belinostat(PXD101,NSC726630,PX-105684) is a novel HDAC inhibitor with IC50 of 27 nM in a cell-free assay,with activity demonstrated in cisplatin-resistant tumors.Belinostat(PXD101)induces autophagy.	price>
R-C-606	SNS-314 cas: 1146618-41-8	SNS-314 is a potent and selective inhibitor of Aurora A,Aurora B and Aurora C with IC50 of 9 nM,31 nM,and 3 nM,respectively.It is less potent to Trk A/B, Flt4,Fms,Axl,c-Raf and DDR2.	price>
R-C-609	p005672HCL cas:1035979-44-2	P5091(P005091)is a selective and potent inhibitor of ubiquitin-specific protease 7(USP7)with EC50 of 4.2 μM and the closely related USP47.	price>
R-C-635	ZCL278 cas:587841-73-4	ZCL-278 is a selective inhibitor of Cdc42.Targets the binding site of the Cdc42 guanine nucleotide exchange factor,intersectin(ITSN).Inhibits Cdc42-mediated cellular effects,including microspike formation in 3T3 fibroblasts and neuronal branching in primary neonatal cortical neurons.Also suppresses cell motility and migration in PC3 cells,without cytotoxic effects.	price>
R-C-648	AT7519HCL cas:902135-91-5	AT7519 Hydrochloride is a potent inhibitor of CDKs,with IC50s of 210,47,100,13, 170,and <10 nM for CDK1,CDK2,CDK4 to CDK6,and CDK9,respectively.	price>
R-C-660	RKI1447 cas:1342278-01-6	RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.	price>
R-C-668	XL413 (BMS-863233) cas: 1169562-71-3	BMS-863233,also known as XL-413,is an orally bioavailable cell division cycle 7 homolog(CDC7)kinase inhibitor with potential antineoplastic activity.	price>
R-C-741	ISRIB CAS : 1597403-47-8	ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.	price>

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