Product apis-autophagy

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Catalog	name	Description	price
R-R-2191	SMER18 CAS No.944153-47-3	SMER18/CAS No.944153-47-3 is a small molecule enhancer of rapamycin which act as a mTOR-independent autophagy inducer.	price>
R-R-2192	CA-5f CAS No.1370032-19-1	CA-5f/CAS No.1370032-19-1 is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity.	price>
R-R-2193	Elaiophylin CAS No.37318-06-2	Elaiophylin (Azalomycin B; Gopalamicin; Efomycin E)/CAS No.37318-06-2 is an autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells.	price>
R-R-2194	Nortriptyline hydrochloride CAS No.894-71-3	Nortriptyline (Desmethylamitriptyline) hydrochloride/CAS No.894-71-3, the main active metabolite of Amitriptyline, is a tricyclic antidepressant. Nortriptyline hydrochloride is a potent autophagy inhibitor and has anticancer effects.	price>
R-R-2195	UBCS039 CAS No.358721-70-7	UBCS039/CAS No.358721-70-7 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM.	price>
R-R-2196	Nortriptyline CAS No.72-69-5	Nortriptyline (Desmethylamitriptyline)/CAS No.72-69-5, the main active metabolite of Amitriptyline, is a tricyclic antidepressant. Nortriptyline is a potent autophagy inhibitor and has anticancer effects.	price>
R-R-2197	Desethyl chloroquine CAS No.1476-52-4	Desethyl chloroquine/CAS No.1476-52-4 is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity.	price>
R-R-2198	S130 CAS No.1160852-22-1	S130/CAS No.1160852-22-1 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC50 of 3.24 µM. S130 suppresses autophagy flux.	price>
R-R-2199	Wogonoside CAS No.51059-44-0	Wogonoside/CAS No.51059-44-0, a flavonoid glycoside isolated from Huangqin, possesses anti-inflammatory effects. Wogonoside induces autophagy in breast cancer cells by regulating MAPK-mTOR pathway.	price>
R-R-2200	Dehydropachymic acid CAS No.77012-31-8	Dehydropachymic acid/CAS No.77012-31-8 is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells.	price>

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