Product apis-autophagy

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Catalog	name	Description	price
R-R-2181	Thonningianin B CAS No.271579-12-5	Thonningianin B/CAS No.271579-12-5 is an antioxidant and an autophagy enhancer.	price>
R-R-2182	Tat-beclin 1 CAS No.1423821-88-8	Tat-beclin 1/CAS No.1423821-88-8, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV).	price>
R-R-2183	Metformin-d6 hydrochloride CAS No.1185166-01-1	Metformin-d6 (hydrochloride)/CAS No.1185166-01-1 is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy.	price>
R-R-2184	Pennogenin 3-O-beta-chacotrioside CAS No.55916-52-4	Pennogenin 3-O-beta-chacotrioside/CAS No.55916-52-4 is an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1. Anti-colorectal cancer activity.	price>
R-R-2185	Aumitin CAS No.946293-78-3	Aumitin/CAS No.946293-78-3 is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively.	price>
R-R-2186	Paclitaxel-d5 (benzoyloxy) CAS No.1261254-56-1	Paclitaxel-d5 (benzoyloxy)/CAS No.1261254-56-1 is the deuterium labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.	price>
R-R-2187	3BDO CAS No.890405-51-3	3BDO/CAS No.890405-51-3 is a new mTOR activator which can also inhibit autophagy.	price>
R-R-2188	Obeticholic acid-d5 CAS No.1992000-80-2	Obeticholic acid-d5/CAS No.1992000-80-2 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy.	price>
R-R-2189	Obeticholic Acid-d4	Obeticholic Acid-d4 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy.	price>
R-R-2190	Venetoclax-d8 CAS No.1257051-06-1	Venetoclax-d8/CAS No.1257051-06-1 is deuterium labeled Venetoclax. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy.	price>

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