Product apis-autophagy

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Catalog	name	Description	price
R-R-2201	Syringin CAS No.118-34-3	Syringin (Eleutheroside B)/CAS No.118-34-3 is an active natural phenolic glycoside possessing various pharmacological activities, including anti-inflammatory, anti-irradiation, anti-osteoporosis and anticancer activities. Syringin also can be used to enhance memory, relieve fatigue, improve human cognition and protect ischemia heart against cerebrovascular damage, etc.	price>
R-R-2202	Ginkgolide K CAS No.153355-70-5	Ginkgolide K/CAS No.153355-70-5, isolated from Ginkgo biloba, induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. Ginkgolide K possesses neuroprotective activity.	price>
R-R-2203	Desethyl chloroquine diphosphate CAS No.247912-76-1	Desethyl chloroquine diphosphate/CAS No.247912-76-1 is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity.	price>
R-R-2204	Zingiberene CAS No.495-60-3	Zingiberene (α-Zingiberene)/CAS No.495-60-3 is a monocyclic sesquiterpene which is the predominant constituent of ginger with oil content (Zingiber officinale). Neuroprotective potential. Zingiberene triggers autophagy. Anticancer activity.	price>
R-R-2205	Glyburide-d3 CAS No.1219803-02-7	Glyburide-d3/CAS No.1219803-02-7 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.	price>
R-R-2206	Metformin hydrochloride CAS No.1115-70-4	Metformin hydrochloride/CAS No.1115-70-4 inhibits the mitochondrial respiratory chain in the liver, it can lead to the activation of AMPK and improve insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy.	price>
R-R-2207	EACC CAS No.864941-31-1	EACC/CAS No.864941-31-1 is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.	price>
R-R-2208	Gartanin CAS No.33390-42-0	Gartanin/CAS No.33390-42-0 is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells.	price>
R-R-2209	DCAP CAS No.500015-20-3	DCAP/CAS No.500015-20-3 is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux.	price>
R-R-2210	Isorhapontigenin CAS No.32507-66-7	Isorhapontigenin/CAS No.32507-66-7, an orally bioavailable dietary polyphenol isolated from the Chinese herb Gnetum cleistostachyum, displays anti-inflammatory effects. Isorhapontigenin induces autophagy and inhibits invasive bladder cancer formation.	price>

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