Catalog |
name |
Description |
price |
R-XASYS-00697 |
AS-35,cas:108427-72-1 |
AS-35(C21H20N6O4,420.42) is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum with IC50 values of 8 nM, 4 nM and 3 nM, respectively, and has antiallergic activities. |
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R-XASYS-00698 |
AS101,cas:106566-58-9 |
AS101(C2H4Cl3O2Te·H4N,312.0), an immunomodulatory tellurium compound, is a potent IL-1β inhibitor. AS101 abolishes phosphorylation of STAT3 by inhibiting IL-10. AS101 potently inhibits Caspase-1 and is used for the autoimmune diseases and certain malignancies. |
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R-XASYS-00699 |
AS-1269574,cas:330981-72-1 |
AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates TRPA1 cation channels to stimulate glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induces glucose-dependent insulin secretion from pancreatic β-cells only under high-glucose conditions. |
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R-XASYS-00700 |
Asapiprant,cas:932372-01-5 |
Asapiprant(C24H27N3O7S,501.6) is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM. |
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R-XASYS-00701 |
Asenapine hydrochloride,cas:1412458-61-7 |
Asenapine hydrochloride(C17H17Cl2NO,322.23), an antipsychotic, is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and Dopamine (D2, D3, D4) receptor antagonist with Ki values of 0.03-4.0 nM for 5-HT and 1.3, 0.42, 1.1 nM for Dopamine receptor, respectively. |
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R-XASYS-00702 |
ASP-9521,cas:1126084-37-4 |
ASP-9521(C19H26N2O3,330.42) is a potent, selective and orally available AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3. |
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R-XASYS-00703 |
Asp-AMS,cas:828288-98-8 |
Asp-AMS(C14H19N7O9S,461.41), an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme. |
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R-XASYS-00704 |
ASP5878,cas:1453208-66-6 |
ASP5878(C18H19F2N5O4,407.37) is an oral active inhibitor of FGFR 1, 2, 3, and 4, with IC50 values of 0.47 nM, 0.6 nM, 0.74 nM and 3.5 nM for FGFR 1, 2, 3, and 4 kinase activity. ASP5878 has potential antineoplastic activity. |
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R-XASYS-00705 |
Aspartyl-alanyl-diketopiperazine,cas:110954-19-3 |
Aspartyl-alanyl-diketopiperazine (C7H10N2O4,186.17) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy. |
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R-XASYS-00706 |
Aspirin Aluminum,cas:23413-80-1 |
Aspirin Aluminum(C18H15AlO9CAS,402.3) is a novel intermolecular compound which can inhibit gastrointestinal mucosal disorders induced by NSAIDs (non-steroidal anti-inflammatory agents) extracted from patent WO 2010064441 A1. |
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