Catalog |
name |
Description |
price |
R-XASYS-00687 |
Arginase inhibitor 1,cas:1345808-25-4 |
Arginase inhibitor 1(C13H27BN2O4,286.18) is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. |
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R-XASYS-00688 |
Arimoclomol maleate,cas:289893-26-1 |
Arimoclomol maleate (C18H24ClN3O7,429.85) is a co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system. |
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R-XASYS-00689 |
ARL67156 trisodium salt,cas:1021868-83-6 |
ARL67156 trisodium salt(C15H24Br2N5O12P3,719.11) is an extracellular ATPase inhibitor. ARL67156 trisodium salt is a weakly competitive inhibitor of NTPCase1 (CD39), NTPCase3, and NPP1, with Ki values of 11, 18, and 12 μM, respectively. ARL67156 trisodium salt can prevent the development of calcified aortic valve disease in vivo. |
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R-XASYS-00690 |
ARN19874,cas:2190502-57-7 |
ARN19874(C19H14N4O4S,394.40) is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor with an IC50 of ~34μM. |
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R-XASYS-00691 |
ARP-100,cas:704888-90-4 |
ARP-100(C17H20N2O5S,364.42) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1 pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50μM), MMP-3 (4.5μM), MMP-7 (>50μM), and MMP-9 (0.2μM). |
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R-XASYS-00692 |
ARQ 531,cas:2095393-15-8 |
ARQ 531 (C25H23ClN4O4,478.93) is a reversible non-covalent and orally active inhibitor of Brutons Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. |
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R-XASYS-00693 |
ARS-1323,cas:1698024-73-5 |
ARS-1323(C21H17ClF2N4O2,430.84), the racemate of ARS-1620, is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1. |
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R-XASYS-00694 |
ARS-853,cas:1629268-00-3 |
ARS-853(C22H29ClN4O3,432.94) is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5μM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation. |
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R-XASYS-00695 |
Artemisone,cas:255730-18-8 |
Artemisone (C19H31NO6S,401.52) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM. Artemisone is also a potent inhibitor of human CMV. |
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R-XASYS-00696 |
Arterolane,cas:664338-39-0 |
Arterolane(C22H36N2O4,392.5) is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively. |
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