Catalog |
name |
Description |
price |
R-XASYS-00677 |
Apararenone,cas:945966-46-1 |
Apararenone (C17H17FN2O4S,364.4) is a novel non-steroidal mineralocorticoid receptor antagonists under development for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis. |
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R-XASYS-00678 |
Apogossypolone,cas:886578-07-0 |
Apogossypolone (C28H26O8,490.50) is an orally active Bcl-2 family proteins inhibitor with Ki values of 35, 25 and 660 nM for Bcl-2, Mcl-1 and Bcl-XL, respectively. Apogossypolone shows antitumor activities, induces cell apoptosis and autophagy. Apogossypolone also has antifungal activity. |
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R-XASYS-00679 |
Apratastat,cas:287405-51-0 |
Apratastat (C17H22N2O6S2,414.50) is an orally active, non-selective and reversible TACE/MMPs inhibitor, can inhibit inhibit the release of TNF-α. Apratastat has the potential to overcome radiotherapy-resistance in non-small cell lung cancer (NSCLC). |
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R-XASYS-00680 |
APY0201,cas:1232221-74-7 |
APY0201(C23H23N7O,413.48) is a potent PIKfyve inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3,5)P2 in the presence of in the presence of [33P]ATP with an IC50 of 5.2 nM. APY0201 also inhibits IL-12/IL-23 production. |
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R-XASYS-00681 |
Apyramide,cas:68483-33-0 |
Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin (HY-14397). Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2. |
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R-XASYS-00682 |
AQ-13 dihydrochloride,cas:169815-40-1 |
AQ-13 dihydrochloride(C16H24Cl3N3,364.74) is an aminoquinoline antimalarial drug that is effective against drug-resistant strains of Plasmodium falciparum. |
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R-XASYS-00683 |
Verosudil,cas:1414854-42-4 |
Verosudil (C17H17N3O2S,327.40) is a potent, selective Rho-kinase (ROCK) inhibitor with Kis of 2 and 2 nM for ROCK1 and ROCK2, respectively. AR-12286 lowers intraocular pressure (IOP) primarily by increasing aqueous humour outflow through the trabecular meshwork. |
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R-XASYS-00684 |
AR-C102222 hydrochloride,cas:1781934-50-6 |
AR-C102222 hydrochloride(C19H17ClF2N6O,418.83) is a potent, competitive, orally active and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 37 nM. AR-C102222 hydrochloride has antinociception and anti-inflammatory activities. |
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R-XASYS-00685 |
Arg-AMS,cas:301351-95-1 |
Arg-AMS (C16H26N10O7S,502.51) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes. |
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R-XASYS-00686 |
Arg-Gly-Asp-Cys,cas:109292-46-8 |
Arg-Gly-Asp-Cys(C15H27N7O7S,449.48) is the binding motif of fibronectin to cell adhesion molecules, and can inhibit platelet aggregation and fibrinogen binding. |
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