AS-1269574,cas:330981-72-1

AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates TRPA1 cation channels to stimulate glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induces glucose-dependent insulin secretion from pancreatic β-cells only under high-glucose conditions.

msds of 2-[[2-(4-bromophenyl)-6-methyl-4-pyrimidinyl]amino]-ethanolmsds of 2-[[2-(4-bromophenyl)-6-methyl-4-pyrimidinyl]amino]-ethanolmsds of 2-[[2-(4-bromophenyl)-6-methyl-4-pyrimidinyl]amino]-ethanol