Catalog name Description price
R-XASYS-00717 Atreleuton,cas:154355-76-7 Atreleuton (C16H15FN2O2S,318.4) is a selective, reversible, and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor. Atreleuton (ABT-761) exhibits potent and selective inhibition of leukotriene formation. price>
R-XASYS-00718 Atrimustine,cas:75219-46-4 Atrimustine(C41H47Cl2NO6,720.72) is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity. price>
R-XASYS-00719 Atropine methyl bromide,cas:2870-71-5 Atropine methyl bromide(C18H26BrNO3,384.3), a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. price>
R-XASYS-00720 AU1235,cas:1338780-86-1 AU1235(C17H19F3N2O,324.34), an adamantyl urea, is a potent MmpL3 inhibitor. The Mycobacterium tuberculosis protein MmpL3 performs an essential role in cell wall synthesis, since it effects the transport of trehalose monomycolates across the inner membrane. price>
R-XASYS-00721 Auglurant,cas:1396337-04-4 Auglurant (C16H12FN5O2,325.30) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration. price>
R-XASYS-00722 Auristatin E,cas:160800-57-7 Auristatin E(C40H69N5O7,732.01) is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin price>
R-XASYS-00723 Aurora Kinase Inhibitor II,cas:331770-21-9 Aurora kinase inhibitor-2(C23H20N4O3,400.4) is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively. price>
R-XASYS-00724 AUT1,cas:1311136-84-1 AUT1(C18H19N3O4,341.4) is a recombinant human Kv3 channel modulator. AUT1 modulates Kv3.1b and Kv3.2a channels in human recombinant with pEC50 values of 5.33 and 5.31 μM, respectively. AUT1 can be used for the research of disorders associated with dysfunction of inhibitory feedback in corticolimbic circuits, such as schizophrenia. price>
R-XASYS-00725 Autogramin-2,cas:2375541-45-8 Autogramin-2(C21H27N3O4S,417.52) potently inhibits autophagy induced by either starvation (IC50=0.27μM) or mTORC1 inhibition (Rapamycin; IC50=0.14μM). price>
R-XASYS-00726 Autotaxin modulator 1,cas:1548743-69-6 Autotaxin modulator 1(C28H31F6NO3,543.54) is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as for researching proliferative disorders such as cancer. price>