Catalog |
name |
Description |
price |
R-XASYS-00737 |
AZ1495,cas:2196204-23-4 |
AZ1495(C21H31N5O2,385.51), a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL). |
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R-XASYS-00738 |
AZ20,cas:1233339-22-4 |
AZ20(C21H24N4O3S,412.5) is a potent and selective inhibitor of ATR with an IC50 of 5 nM, and has 8-fold selectivity against mTOR (IC50=38 nM). |
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R-XASYS-00739 |
AZ304,cas:942507-42-8 |
AZ304(C27H25N5O2,451.52) is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively. AZ304 also has significant effect on other kinases, such as p38 (IC50, 6 nM), CSF1R (IC50, 35 nM). |
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R-XASYS-00740 |
AZ505 ditrifluoroacetate,cas:1035227-44-1 |
AZ505 ditrifluoroacetate(C33H40Cl2F6N4O8,805.59) is a potent and selective SMYD2 inhibitor with IC50 of 0.12μM. |
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R-XASYS-00741 |
AZ7550,cas:1421373-99-0 |
AZ7550(C27H31N7O2,485.6) is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6μM. |
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R-XASYS-00742 |
AZ82,cas:1449578-65-7 |
AZ82(C28H31F3N4O3S,560.6) is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1. |
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R-XASYS-00743 |
Azaphen,cas:24853-80-3 |
Pipofezine(Azafen or Azaphen)(C16H21Cl2N5O,370.28) is a potent inhibitor of the reuptake of serotonin. |
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R-XASYS-00744 |
Azaserine,cas:115-02-6 |
Azazerine (C5H7N3O4,173.1) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic, it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection. |
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R-XASYS-00745 |
Azasetron HCl,cas:123040-16-4 |
Azasetron (Y-25130) hydrochloride(C17H20ClN3O3·HCl,386.27), a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV) |
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R-XASYS-00746 |
Azatadine,cas:3964-81-6 |
Azatadine(C20H22N2,290.40) is a benzo[5,6]cyclohepta[1,2-b]pyridine having a 1-methylpiperidin-4-ylidene group at the 11-position. It has a role as a H1-receptor antagonist and an anti-allergic agent. It is a benzocycloheptapyridine and a tertiary amine. |
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