| Catalog | name | Description | price |
|---|---|---|---|
| R-XASYS-00406 | (-)-Hydroxycitric acid,cas:27750-10-3 | (-)-Hydroxycitric acid(C6H8O8,208.12) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty acid synthesis, food intake, lipogenesis, and induced weight loss. | price> |
| R-XASYS-00407 | (2R,3R)-3,7,4-Trihydroxy-5-methoxy-8-prenylflavanone,cas:204935-85-3 | (2r,3r)-3,7,4-Trihydroxy-5-methoxy-8-prenylflavanone(C21H22O6,370.401) is a natural product found in Marshallia grandiflora with data available. | price> |
| R-XASYS-00408 | Indirubin-3-oxime,cas:667463-82-3 | Indirubin-3-monoxime(C16H11N3O2,277.283) is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimers disease. | price> |
| R-XASYS-00409 | hDHODH-IN-1,cas:1173715-42-8 | hDHODH-IN-1(C17H14N2O2,278.311) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect. | price> |
| R-XASYS-00410 | (3R,4R)-A2-32-01,cas:1359752-95-6 | (3R,4R)-A2-32-01 (compound 2)(C19H27NO2,301.42) is a specific caseinolytic protein proteases (ClpP) inhibitor (EC50: 4.5μM). | price> |
| R-XASYS-00411 | ML-211,cas:2205032-89-7 | ML-211(C25H30N4O2,418.541) is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM) | price> |
| R-XASYS-00412 | DHODH-IN-11,cas:1263303-95-2 | DHODH-IN-11(C15H11N3O2,265.27) is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03. | price> |
| R-XASYS-00413 | TBCA,cas:934358-00-6 | TBCA(C9H4Br4O2,463.7) is a selective, cell-permeable inhibitor of CK2 (IC50 = 0.11 µM, Ki = 77 nM) that has minimal effect on a panel of 28 other kinases. It induces cell death in Jurkat adult T cell leukemia cells (DC50 = 7.7 µM), driving caspase-dependent degradation of poly-ADP ribose polymerase while inhibiting CK2 activity. | price> |
| R-XASYS-00414 | Tripolin A,cas:1148118-92-6 | Tripolin A(C15H11NO3,253.3) is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5μM and 7μM, respectively) | price> |
| R-XASYS-00415 | (E/Z)-GO289,cas:694522-87-7 | (E/Z)-GO289(C17H15BrN4O2S,419.3), which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity. | price> |

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