(E/Z)-GO289,cas:694522-87-7

(E/Z)-GO289(C17H15BrN4O2S,419.3), which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.

msds of (E Z)-GO289