Product fluorescent-dyes-No-ROS-Rox-derivatives

Home > products > fluorescent-dyes> No-ROS-Rox-derivatives

Catalog	name	Description	price
R-XASYS-00396	Aucubin,cas:479-98-1	Aucubin(C15H22O9,346.3) is an iridoid glycoside that has been found in E. ulmoides with diverse biological activities.Aucubin (0.001-1μg/ml) dose-dependently inhibits the IgE-stimulated secretion of IL-6 and TNF-αby RBL-2H3 mast cells (IC50s = 0.19 and 0.1μg/ml, respectively).	price>
R-XASYS-00397	DAz-2,cas:1176905-54-6	DAz-2(C9H13N3O2,195.2) is a cell-permeable chemical probe used to detect cysteine oxidation in proteins. Redox-sensitive cysteine residues in proteins may function as sensors of reactive oxygen species (ROS) and also serve as molecular switches, activating or deactivating proteins, following a change in oxidation state. Modification of protein function through the reversible oxidation of cysteine is emerging as a biologically relevant signal transduction mechanism.	price>
R-XASYS-00398	Astilbin,cas:29838-67-3	Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities.It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200μM.	price>
R-XASYS-00399	Citrinin,cas:518-75-2	Citrinin(C13H14O5,250.3) is a mycotoxin that has been found in Monascus and has diverse biological activities.It is active against S. aureus, methicillin-resistant S. aureus (MRSA), rifampicin-resistant S. aureus, and vancomycin-resistant E. faecium (MICs = 1.95, 3.9, 0.97, and 7.81 µg/ml, respectively), as well as the pathogenic yeast C. neoformans (MIC = 3.9 µg/ml).	price>
R-XASYS-00400	BCI (hydrochloride),cas:95130-23-7	BCI(C22H23NO•HCl,353.9) is an inhibitor of dual specificity phosphatase 6 (DUSP6) and DUSP1.1,2 (E/Z)-BCI (0.5-2 µM) inhibits LPS-induced expression of Dusp6 in a concentration-dependent manner and increases nuclear protein levels of Nrf2 in RAW 264.7 macrophages.	price>
R-XASYS-00401	Pyrroloquinoline quinone,cas:72909-34-3	Pyrroloquinoline quinone (PQQ)(C14H6N2O8,330.2) is a quinone and redox enzyme cofactor that has been found in a variety of bacteria and has diverse biological activities.It inhibits fibril formation by the amyloid proteins amyloid-β (1-42) (Aβ42) and mouse prion protein when used at a concentrations of 100 and 300 μM.	price>
R-XASYS-00402	(+)-WIN 55,212-2 (mesylate),cas:131543-23-2	(+)-WIN 55,212-2 (mesylate)(C27H26N2O3·CH3SO3H,522.6) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Ki values of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively.In primary cultures of rat cerebral cortex neurons, (+)-WIN 55,212-2 (mesylate) (0.01-100 nM) increases extracellular glutamate levels, displaying a bell-shaped concentration-response curve.	price>
R-XASYS-00403	(–)-Blebbistatin,cas:856925-71-8	(–)-Blebbistatin(C18H16N2O2,292.3) is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin.It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 µM), while poorly inhibiting smooth muscle myosin (IC50 = 80 µM).	price>
R-XASYS-00404	(-)-Terreic Acid,cas:121-40-4	Terreic acid (TA)(C7H6O4,154.1) is a cell-permeable quinone epoxide that selectively inhibits Brutons tyrosine kinase (BTK) catalytic activity (IC50s = 10 and 3 µM for basal and activation levels, respectively).	price>
R-XASYS-00405	(-)-Syringaresinol 4-O-β-D-glucopyranoside,cas:137038-13-2	(-)-Syringaresinol(C28H36O13,580.583) inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemotherapeutic agent for the treatment of cancer.	price>

...