Catalog name Description price
R-XASYS-00418 R(-)-N-Allylnorapomorphine,cas:18426-17-0 R(-)-N-Allylnorapomorphine(C19H19NO2,293.4) is a potent inhibitor of the single-strand DNA cytosine deaminase APOBEC3G , with an IC 50 of 2.9 μM. R(-)-N-Allylnorapomorphine also is a dopamine receptor antagonist. R(-)-N-Allylnorapomorphine can reduce renal hypoxia-reoxygenation injury. price>
R-XASYS-00419 (R)-Elagolix,cas:834153-87-6 (R)-Elagolix(C32H30F5N3O5,631.59) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. price>
R-XASYS-00420 (R)-Filanesib,cas:885060-08-2 (R)-Filanesib(C20H22F2N4O2S,420) is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM). price>
R-XASYS-00421 (R)-Gyramide A (hydrochloride),cas:1793050-70-0 (R)-Gyramide A( C21H27FN2O3S•HCl,1793050-70-0) is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM.It does not affect the closely related enzyme topoisomerase IV. price>
R-XASYS-00422 (R)-P7C3-Ome,cas:1235481-43-2 (R)-P7C3-Ome(C22H20Br2N2O2,504.2) is a hydroxylated analog of the proneurogenic and neuroprotective compound P7C3-A20. price>
R-XASYS-00423 (Rac)-LM11A-31 dihydrochloride,cas:1214672-15-7 (Rac)-LM11A-31 dihydrochloride(C12H27Cl2N3O2,316.27) is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist. price>
R-XASYS-00424 (Rac)-Plevitrexed,cas:153538-08-0 (Rac)-Plevitrexed(C26H25FN8O4,532.53) is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS). price>
R-XASYS-00425 BAY-218,cas:2162982-11-6 BAY-218 (AHR antagonist ) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 μM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses. price>
R-XASYS-00426 (S)-Crizotinib,cas:1374356-45-2 (S)-Crizotinib(C21H22Cl2FN5O,450.3) is an inhibitor of muT homolog (MTH1; IC50 = 72 nM).It is selective for MTH1 over a panel of 456 kinases at 1 µM. (S)-Crizotinib (30 µM) induces oxidative DNA damage and apoptosis in SGC-7901 and BGC-823 human gastric cancer cells. price>
R-XASYS-00427 (S)-ML753286,cas:1699720-85-8 (S)-ML753286(C20H25N3O3,335) is a research tool that activates the receptor and cell biology. It is an activator of Ligand and Receptor, which can be used in Cell Biology, Antibody, Ion channels, High purity, Protein interactions, Pharmacology and Peptides. The chemical formula of (S)-ML753286 is C17H22N2O3 with a molecular weight of 288.32 g/mol. price>