Catalog name Description price
R-XASYS-00416 (E/Z)-GSK-3βinhibitor 1,cas:3367-88-2 GSK-3βinhibitor 1(C14H10N2O,222.2) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy. price>
R-XASYS-00417 D-a-Hydroxyglutaric Acid,cas:13095-47-1 D-α-Hydroxyglutaric acid (D-2-HG)(C5H8O5,148.1) is anα-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA).It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT). price>
R-XASYS-00418 R(-)-N-Allylnorapomorphine,cas:18426-17-0 R(-)-N-Allylnorapomorphine(C19H19NO2,293.4) is a potent inhibitor of the single-strand DNA cytosine deaminase APOBEC3G , with an IC 50 of 2.9 μM. R(-)-N-Allylnorapomorphine also is a dopamine receptor antagonist. R(-)-N-Allylnorapomorphine can reduce renal hypoxia-reoxygenation injury. price>
R-XASYS-00419 (R)-Elagolix,cas:834153-87-6 (R)-Elagolix(C32H30F5N3O5,631.59) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. price>
R-XASYS-00420 (R)-Filanesib,cas:885060-08-2 (R)-Filanesib(C20H22F2N4O2S,420) is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM). price>
R-XASYS-00421 (R)-Gyramide A (hydrochloride),cas:1793050-70-0 (R)-Gyramide A( C21H27FN2O3S•HCl,1793050-70-0) is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM.It does not affect the closely related enzyme topoisomerase IV. price>
R-XASYS-00422 (R)-P7C3-Ome,cas:1235481-43-2 (R)-P7C3-Ome(C22H20Br2N2O2,504.2) is a hydroxylated analog of the proneurogenic and neuroprotective compound P7C3-A20. price>
R-XASYS-00423 (Rac)-LM11A-31 dihydrochloride,cas:1214672-15-7 (Rac)-LM11A-31 dihydrochloride(C12H27Cl2N3O2,316.27) is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist. price>
R-XASYS-00424 (Rac)-Plevitrexed,cas:153538-08-0 (Rac)-Plevitrexed(C26H25FN8O4,532.53) is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS). price>
R-XASYS-00425 BAY-218,cas:2162982-11-6 BAY-218 (AHR antagonist ) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 μM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses. price>