Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00436	SR7826,cas:1219728-20-7	SR 7826(C22H21N5O2,387.43) is a potent and selective LIMK inhibitor (IC50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro.	price>
R-XASYS-00437	SB 225002,cas:182498-32-4	SB 225002(C13H10BrN3O4,352.1) is a selective non-peptide inhibitor of CXCR2, inhibiting IL-8 binding to CXCR2 with an IC50 value of 22 nM.SB225002 inhibits neutrophil chemotaxis in response to IL-8 in vitro (IC50 = 20 nM) and blocks neutrophil margination induced by IL-8 in vivo (IC50 = 30 nM).	price>
R-XASYS-00438	RS-25344 hydrochloride,cas:152815-28-6	RS 25344 hydrochloride(C19H14ClN5O4,411.8) is a phosphodiesterase (PDE) 4 inhibitor	price>
R-XASYS-00439	CMP-5,cas:880813-42-3	CMP-5(C21H21N3,315.41) is a potent and selective PRMT5 inhibitor that is inactive against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity during histone preparation.	price>
R-XASYS-00440	FEN1-IN-4,cas:1995893-58-7	FEN1-IN-4 (Compound 2)(C12H12N2O3,232.24) is a human flap endonuclease-1 (hFEN1) inhibitor	price>
R-XASYS-00441	PKA-IN-1,cas:179985-52-5	1-Acetamido-4-cyano-3-methylisoquinoline(C13H11N3O,225.25) is a selective inhibitor of PKA (cyclic AMP-dependent protein kinase).	price>
R-XASYS-00442	1-acetyl-3,2-toluyl-5-fluorouracil,cas:71861-76-2	1-Acetyl-3-o-toluyl-5-fluorouracil (A-OT-Fu)(C14H11FN2O4,290.25) is a potent an antineoplastic agent.	price>
R-XASYS-00443	1-Azakenpaullone,cas:676596-65-9	1-Azakenpaullone(C15H10BrN3O,328.2) is an analog of kenpaullone that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).	price>
R-XASYS-00444	1-Deazaadenosine,cas:14432-09-8	1-Deazaadenosine(C11H14N4O4,266.25) is a nitro compound that binds to adenosine receptors and has antiviral activity. It inhibits the growth of herpes simplex virus and lymphoproliferative disorders, which are caused by adenosine receptor subtypes. 1-Deazaadenosine also binds to the hydrogen bond between the amine group of adenosine and the hydroxyl group of water, forming an intramolecular hydrogen bond.	price>
R-XASYS-00445	5-Lipoxygenase-in-1,cas:125235-15-6	5-Lipoxygenase-in-1(C23H28N4O2S,424.56) is a recombinant peptide that is used as a research tool in cell biology and pharmacology. It has been shown to be an inhibitor of 5-lipoxygenase (5LOX) and may have potential therapeutic value for the treatment of inflammation, asthma, atherosclerosis, and other diseases related to eicosanoid synthesis.	price>

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