Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00031	8-Hydroxyguanine (hydrochloride),cas:1246818-54-1	8-Hydroxyguanine(C5H5N5O2•HCl,203.6) is produced by oxidative degradation of DNA by hydroxyl radical. It serves as a measure of oxidative stress in biological systems.	price>
R-XASYS-00032	9,10-Anthracenediyl-bis(methylene)dimalonic Acid,cas:307554-62-7	9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA)(C22H18O8,410.4) is a reagent used to detect singlet oxygen generation. This water-soluble derivative of anthracene can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease in optical density at 400 nm (ABMDMA ex/em max. = 380/407 nm in 0.1 M phosphate pH 7.0).	price>
R-XASYS-00033	Alibiflorin,cas:39011-90-0	Albiflorin(C23H28O11,480.46) is a major constituent contained in peony root; possesses therapeutic potential for neurodegenerative diseases.IC50 value:Target: in vitro: Albiflorin significantly ameliorated Glu-induced reduction of cell viability, nuclear and mitochondrial apoptotic alteration, reactive oxygen species accumulation, and B-cell lymphoma 2 (Bcl-2)/Bax ratio. Albiflorin also enhanced phosphorylation of AKT and its downstream element glycogen synthase kinase-3β, and this effect was abrogated by the AKT inhibitor LY294002.	price>
R-XASYS-00034	alpha-Mangostin,cas:6147-11-1	α-Mangostin(C24H26O6,410.46) is a xanthone that has been found in G. mangostana and has diverse biological activities.It inhibits fatty acid synthase and HIV-1 protease (IC50s = 5.54 and 5.12 μM, respectively).α-Mangostin is active against methicillin-sensitive and -resistant S. aureus strains (MICs = 1.57-12.5 μg/ml).It inhibits nitric oxide and prostaglandin E2 production in LPS-stimulated RAW 264.7 cells (IC50s = 12.4 and 11.08 μM, respectively)	price>
R-XASYS-00035	Amentoflavone,cas:1617-53-4	Amentoflavone(C30H18O10,538.46) is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects.IC50 value:Target:In vitro: In irradiated v79 cells, Pretreatment with amentoflavone 24 hours prior to 8 Gy 60Co γ-ray irradiation significantly inhibited apoptosis, promoted the G2 phase, decreased the concentration of ROS and mitochondrial mass. Amentoflavone dose-dependently inhibited the viability of SW480 cells, and a high concentration of amentoflavone (150 μmol/L) obviously induced apoptosis of the cells.	price>
R-XASYS-00036	AMK (hydrochloride),cas:1215711-91-3	AMK(C12H16N2O3·HCl,272.7) is an active metabolite of the neurohormone melatonin.It is formed from melatonin via the metabolic intermediate AFMK that is then deformylated by catalase or formamidase.AMK scavenges singlet oxygen in vitro when used at a concentration of 200 µM.	price>
R-XASYS-00037	APF,cas:359010-70-1	APF(C26H17NO5,423.4) is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants.	price>
R-XASYS-00038	Arimoclomol,cas:289893-25-0	Arimoclomol(C14H20ClN3O3,313.8) is a co-inducer of heat shock proteins (Hsps).It increases pancreatic Hsp60 and Hsp70 levels, decreases malondialdehyde (MDA) and protein carbonyl levels, increases glutathione peroxidase (GPX) activity, and decreases Cu/Zn superoxide dismutase (SOD) activity in a rat model of cholecystokinin (CCK) octapeptide-induced acute pancreatitis when administered at a dose of 20 mg/kg.	price>
R-XASYS-00039	Arjunolic Acid,cas:465-00-9	Arjunolic acid(C30H48O5,488.7) is a triterpene that has been found in T. arjuna and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties.It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay when used at a concentration of 0.8 mM.Arjunolic acid (20 mg/kg for four days) prevents arsenic-induced decreases in the activity of superoxide dismutase (SOD1), catalase, GST, and glutathione reductase in mouse brain.	price>
R-XASYS-00040	Biliverdin (technical grade),cas:114-25-0	Biliverdin(C33H34N4O6,582.7) is a porphyrin bile pigment and precursor in the biosynthesis of bilirubin.It is formed via oxidative catabolism of heme by heme oxygenase-1 (HO-1) and further reduced to bilirubin by biliverdin reductase. Biliverdin has antioxidant activity in oxygen radical absorbance capacity (ORAC) and Trolox equivalent absorbance capacity (TEAC) assays when used at concentrations greater than 0.5 µM.	price>

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