Product apis-transmembrane-transporters

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Catalog	name	Description	price
R-C-2318	CM 4620 CAS:1713240-67-5	CM 4620 is an inhibitor of calcium-release activated calcium-channel(CRAC channel).CM4620 inhibits Orai1/STIM1-mediated Ca2+ currents and Orai2/STIM1-mediated currents with IC50 of near 120 nM and 900 nM.	price>
R-C-2319	Columbianadin CAS:5058-13-9	Columbianadin(Zosimin,2-Butenoic acid),a natural coumarin from Angelica decursiva,is known to have various biological activities including calcium-channel blocking activity,cytotoxic activity against various cancer cell lines,analgesic activities,intestinal absorption and transportation,anti-inflammatory and anti-cancer effects.	price>
R-C-2320	Tetrandrine (NSC-77037) CAS:518-34-3	Tetrandrine(NSC-77037;d-Tetrandrine)is a bis-benzyl-isoquinoline alkaloid,which inhibits voltage-gated Ca2+ current(ICa)and Ca2+-activated K+ current.	price>
R-C-2323	Rhynchophylline CAS:76-66-4	Rhynchophylline(Mitrinermine),an active component isolated from species of the genus Uncaria,acts as a calcium channel blocker and is widely used in traditional Chinese medicine mainly for treating ailments of central nervous and cardiovascular systems,such as lightheadedness,convulsions,numbness,and hypertension.	price>
R-C-2324	Levamlodipine CAS:103129-82-4	Levamlodipine((S)-Amlodipine)is a powerful dihydropyridine calcium channel blocker,possessing vasodilation properties and used in the treatment of hypertension and angina.	price>
R-C-2325	Protopine CAS:130-86-9	Protopine(Corydinine,Fumarine,Biflorine,Macleyine),an alkaloid present in different plants,has been shown to exhibit a number of activities,such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation.It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.	price>
R-C-2326	Trimethadione CAS:127-48-0	Trimethadione(3,5,5,-Trimethyloxazolidine-2,4-dione)is an oxazolidinedione anticonvulsant agent widely used against absences seizures.Trimethadione also is a T-type calcium channel blocker which has antihyperalgesic effects.	price>
R-C-2327	SN-6 CAS: 415697-08-4	SN-6 is a selective Na+/Ca2+ exchanger(NCX)inhibitor.SN-6 inhibits NCX1,NCX2, and NCX3 with IC50 of 2.9μM,16μM and 8.6μM, respectively.SN-6 abolishes acetylcholine(ACh)-induced vasodilation.	price>
R-C-2328	Pinaverium bromide CAS:53251-94-8	Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract,effectively relieves pain,diarrhea and intestinal discomfort,provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome(IBS)patients.	price>
R-C-2329	Strontium Ranelate CAS:135459-87-9	Strontium Ranelate(S12911)is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation,thereby inducing a positive bone balance.Strontium Ranelate also can activate the calcium-sensing receptor (CaSR)in non skeletal cells,resulting in the activation of inositol 1,4,5-triphosphate production and mitogen-activated protein kinase signaling.	price>

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