Product apis-transmembrane-transporters

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Catalog	name	Description	price
R-C-2306	Nimodipine CAS:66085-59-4	Nimodipine(BAY-e 9736)is an orally active,well-tolerated and light-sensitive dihydropyridine calcium antagonist.Nimodipine can be used for the research of cerebrovascular disorders.	price>
R-C-2307	Nilvadipine CAS: 75530-68-6	Nilvadipine is a calcium channel blocker(CCB)used for the treatment of hypertension and chronic major cerebral artery occlusion.Pathohistochemical studies have revealed that the volume of the infarction in the middle cerebral artery occlusion model could be decreased by nilvadipine.Nilvadipine has also been studied as a possible treatment for Alzheimer is Disease.	price>
R-C-2308	Lacidipine CAS:103890-78-4	Lacidipine is a dihydropyridine L-type calcium channel blocker.It induces relaxation of isolated rat aorta and inhibits calcium-induced contraction of rabbit ear artery.It also induces relaxation of calcium-induced contractions in isolated rat colon and bladder and guinea pig trachea. Lacidipine induces negative inotropy in isolated guinea pig ventricular strips.It reduces mean blood pressure in spontaneously hypertensive rats and in renal hypertensive dogs with a transient increase in heart rate.Lacidipine inhibits copper-induced oxidation of isolated human LDL when used at concentrations of 1 and 5µM.It reduces the extension of aortic atheromatous lesions and decreases renal injury in ApoE-/-mice in a model of Western diet-induced atherosclerosis.	price>
R-C-2309	Nifedipine (BAY-a-1040) CAS:21829-25-4	Nifedipine is a medication used to manage angina,high blood pressure,Raynaud is phenomenon,and premature labor.It is one of the treatments of choice for Prinzmetal angina.It may be used to treat severe high blood pressure in pregnancy.Its use in preterm labor may allow more time for steroids to improve the baby is lungs and time to transfer the mother to a well qualified medical facility before delivery.Nifedipine is taken by mouth and is sold in fast and slow release formulations.	price>
R-C-2310	Clevidipine Butyrate CAS:167221-71-8	Clevidipine is a short-acting dihydropyridine calcium channel antagonist(IC50=7.1nM,V(H)=-40mV)under development for treatment of perioperative hypertension.	price>
R-C-2311	Nitrendipine CAS:39562-70-4	Nitrendipine(BAY-E-5009),an analogue of Nifedipine(HY-B0284),is a dihydropyridine calcium channel blocker with vasodilator action.Nitrendipine has antihypertensive effect.	price>
R-C-2313	Cinepazide maleate CAS:26328-04-1	Cinepazide Maleate(MD-67350)is a piperazine derivative and acts as a weak calcium channel blocker.Cinepazide Maleate is a potent vasodilator and can be used for the research of cerebrovascular diseases,including ischemic stroke,brain infarct et.al.	price>
R-C-2314	Nicardipine CAS:55985-32-5	Nicardipine(YC-93 free base)is a calcium channel blocker with an IC50 of 1μM for blocking cardiac calcium channels.Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure.	price>
R-C-2316	Efonidipine CAS:111011-63-3	Efonidipine(NZ-105)is an L-and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart.It also suppresses aldosterone secretion from the adrenal.	price>
R-C-2317	Panaxadiol CAS:19666-76-3	Panaxadiol(20(R)-Panaxadiol)is a triterpene sapogenin originally found in species of Panax(ginseng)and exhibits anticancer,cardioprotective,anti-arrhythmic,and antioxidative activities.It inhibits Ca2+ channels,decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential.	price>

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