Catalog |
name |
Description |
price |
R-DS-0093 |
DSPE-PEG-An1 |
Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology. |
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R-DS-0007 |
DSPE-PEG-EB1 |
Liposomes have the advantages of low toxicity,easy preparation,being both the carrier of water-soluble drugs and the carrier of liposoluble drugs,suitable for various drug delivery routes,improving the stability of drugs and achieving targeted drug delivery.However,when liposomes enter the body,due to the specific regulation of plasma conditioner on liposomes,and the nonspecific hydrophobic effect between the cells of the reticuloendothelial system (RES) and liposomes, it is easy to be absorbed and removed by res cells.The half-life of the liposomes is shorter (generally 30 minutes),and the active targeting and stability are poor,Its application is limited to improve its stability in blood circulation,change the biological distribution of liposomes,and have targeted. |
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R-DS-0094 |
DSPE-PEG-RMP-7(receptor-mediated permeabilizer-7) |
Bradykinin or RMP-7 can not only increase the transport of anticancer drugs,but also promote gene therapy virus, non viral vector,cytokines into human brain tumor tissue,and improve the lethality of tumor cells and tumor cells in the surrounding infiltration area.Bradykinin or RMP-7 not only can selectively open BTB, but also can promote the peripheral opioid receptor agonist loperamide to pass through the normal BBB to produce central analgesic effect.In the animal model of Parkinson disease,RMP-7 can promote cyclosporine A to pass through the blood-brain barrier and make a small dose of cyclosporine A (CSA) produce neuroprotective effect. |
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R-DS-0008 |
DSPE-PEG-PF6 |
(DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.One of the important characteristics of cell penetrating peptides (CPPS) is that they can carry a variety of bioactive substances with different sizes and properties into cells,including small molecule compounds,dyes,chromatography,nucleic acids (peptide nucleic acids, PNA),proteins,plasmid DNA,siRNA,200 nm liposomes,phage particles and superparamagnetic particles. |
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R-DS-0095 |
DSPE-PEG2000-B6 |
Cell penetrating peptide (CPP) is a kind of short peptide with strong penetration effect on cell membrane,which can promote cell uptake.Liposome modified by CPP can improve the rate of liposome entry into the cell,which is a new direction of targeted drug delivery carrier research.The amphiphilic block lipid molecule dspe-peg2000-b6 modified by cell osmotic peptide B6 prolonged the blood circulation time,promoted the penetration of nanoparticles (NPS) through BBB,and effectively enriched the drug loaded NPs in glioma lesions. |
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R-DS-0009 |
DSPE-PEG-NGR(Asn-Gly-Arg) |
Aminopeptidase N is a protease preferentially expressed in vascular endothelial cells.NgR sequence can promote the binding of peptide to aminopeptidase N. |
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R-DS-0096 |
LCDX-PEG-DSPE |
DSPE-PEG peptide customization-phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China.Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field. |
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R-DS-0010 |
DSPE-PEG-APRPG(ALA Pro Arg Pro Gly) |
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Polyethylene glyco-APRPG(ALA Pro Arg Pro Gly),APRPG(ALA Pro Arg Pro Gly),namely alanine proline arginine proline glycine sequence,can specifically act on the neovascularization site of tumor,and can be used as a probe to actively target the neovascularization.Aprpg modified liposomes are beneficial to deliver the encapsulated drugs to the vasculogenic vasculature system.The anti-tumor angiogenesis therapy with aprpg modified liposome can target almost all solid tumors actively without drug tolerance.It is a new and efficient anti-tumor method. |
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R-DS-0097 |
HE2-PEG2000-DSPE |
DSPE-PEG peptide customization-phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China. Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field. |
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R-DS-0011 |
DSPE-PEG-VIP(vasoactive intestinal peptide) |
Vasoactive intestinal peptide (VIP) is a basic peptide composed of 28 amino acid residues.It belongs to the gastrin/VIP family of gastrointestinal peptide hormones.It is widely distributed in the body,and has high content in the gastrointestinal tract,central and peripheral nerve endings,and has a wide range of physiological functions. |
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