Catalog |
name |
Description |
price |
R-DS-0085 |
pCPP-PEG-DSPE(CKRRMKNvocWKNvo0cKNvoc) |
PCPP could increase the titers of IgM,IgG and IgG1 of influenza antigen by at least 10 times.The amount of PCPP adjuvant was positively correlated with the molecular weight of the polymer. |
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R-DS-0086 |
DSPE-PEG2000-YSA |
The preparation and characterization of siRNA loaded ysa peptide modified nanostructured lipid carriers (siRNA/ysa-nlc) were studied.Dspe-peg2000-ysa was prepared by the reaction of ysa and dspe-peg2000 mal;NLC was prepared by melt ultrasonic method;the surface of NLC was modified by synthesized dspe-peg2000-ysa to prepare ysa-nlc,which was compounded with siRNA,The optimal amount of dspe-peg2000-ysa was screened by MCF-7 cells,and the optimized siRNA/ysa-nlc was characterized. |
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R-DS-0087 |
DSPE-PEG-ATWLPPR |
DSPE co rotating polyethylene glycol is a kind of phospholipid and polyethylene glycol.The combination of glycol has hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.Pegylated cationic liposomes were modified with D4,a small molecular peptide ligand targeting epidermal growth factor receptor (EGFR),and its effect on transfection efficiency of tumor cells was found by observing the improvement of plasmid DNA and siRNA. |
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R-DS-0001 |
DSPE-PEG_(2000)-RVG-15(YTIWCDIFTNSRGKR) |
Rabies virus glycoprotein derived peptide 15 (rvg-15) peptide was linked to polyethylene glycol phosphatidylethanolamine (peg-dspe),and a brain targeting vector,polyethylene glycol phosphatidylethanolamine(DSPE-PEG),was synthesized_ (2000)-rvg-15)can solve the bottleneck problem of small molecule chemical drugs entering the brain and reduce the systemic side effects. |
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R-DS-0088 |
DSPE-PEG2000-CpG |
Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology. |
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R-DS-0002 |
DSPE-PEG-RR-8(H-RRRRRRRR-NH2) |
Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides. |
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R-DS-0003 |
DSPE-PEG-R6H4 |
One of the important characteristics of cell penetrating peptides (CPPS) is that they can carry a variety of bioactive substances with different sizes and properties into cells,including small molecule compounds,dyes,chromatography, nucleic acids (peptide nucleic acids,PNA),proteins,plasmid DNA,siRNA,200 nm liposomes,phage particles and superparamagnetic particles.This property makes CPPs become alternative drugs It is possible to use a good carrier. |
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R-DS-0090 |
DSPE-PEG-D-PMIα |
Ruixi Biotechnology Co.,Ltd.is a well-known biotechnology company in China.At present, the main products of the company are synthetic phospholipids,PEG derivatives,block copolymers,gold nanoparticles,magnetic nanoparticles, mesoporous silica,reactive fluorescent dyes,fluorescent quantum dots,click chemistry and macrocyclic ligands and so on.These products are widely used in hundreds of laboratories and universities in China Ten Chinese scientific research institutes and pharmaceutical factories supply them for a long time. |
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R-DS-0004 |
DSPE-PEG-TH(AGYLLGHINLHHLAHL) |
A pH responsive cell penetrating peptide modified liposome th lip was synthesized by introducing th into liposomes.Due to the pH sensitivity of th, the transmembrane activity of th is masked in blood circulation and normal tissues;when th lip reaches tumor tissue,histidine in th sequence is protonated, which makes the surface charge of th lip turn from negative to positive, and the transmembrane activity of th is activated,which increases the uptake of th lip by tumor cells.In vitro studies showed that paclitaxel loaded liposome PTX th lip could effectively inhibit the growth of tumor cells and induce apoptosis in a pH dependent manner. |
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R-DS-0091 |
DMPE-PEG5000-pCF1-CFTR |
DMPE is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.PEGylation of phospholipid significantly improved the blood circulation time and stability of capsule drugs.Polyethylene glycol can enhance solubility and stability,reduce the surface nonspecific binding of charged molecules,and reduce the immunogenicity of peptides. |
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